Some nucleoside analogues currently used as antiretroviral agents might promote mutagenesis
besides their putative ability to interfere with endogenous nucleotide metabolism and/or …

… Substitution of a terminal phenyl residue in the side chain blocking group with a p-nitrophenyl
residue further enhances apparent affinity to PEPT1. With regard to PEPT2, specific …

The human concentrative nucleoside transporter (hCNT) protein family has three members,
hCNT1, 2, and 3, encoded by SLC28A1, A2, and A3 genes, respectively. hCNT1 and hCNT2 …

… Two naturally occurring pyrimidine nucleosides, cytidine and thymidine, significantly inhibited
uridine transport when used at a concentration of 100 µM (P<0.001), far above their known …

Nucleoside transporters (NTs) mediate the uptake of nucleosides and nucleobases across
the plasma membrane, mostly for salvage purposes. The canonical NTs belong to two gene …

A novel cloned polymorphism of the human concentrative nucleoside transporter hCNT3 was
described and functionally characterized. This variant consists of a T/C transition leading to …

Nucleoside analogues are broadly used in cancer treatment. Although nucleoside metabolism
is a necessary step in the development of their cytotoxicity, mediated transport across the …

Background Nucleoside transporter proteins (NTs) encoded by members of the SLC28 and
SLC29 gene families contribute to nucleoside and nucleobase recycling but also modulate …

Nucleoside transporters (NTs) are involved in the cytotoxicity and transcriptomic response
induced by nucleoside analogues. A relationship between the expression of nucleoside …

… P value obtained using the Student's t-test for both pcDNA3-hCNT1S546 and pcDNA3-…
P. Cano-Soldado was a recipient of a FPI fellowship from MICINN, Spain. E. Gorraitz was a …