Since the introduction of insulin almost a century ago, more than 80 peptide drugs have
reached the market for a wide range of diseases, including diabetes, cancer, osteoporosis, …

Peptide therapeutics are acclaimed as a promising addition to the pharmaceutical arena,
and they continue to attract interest due to their high potency, bioavailability, and fewer …

The remarkable potency and pharmacological diversity of animal venoms has made them
an increasingly valuable source of lead molecules for drug and insecticide discovery. …

Venomous animals are thought to inject the same combination of toxins for both predation
and defence, presumably exploiting conserved target pharmacology across prey and …

Cone snails use venom containing a cocktail of peptides ('conopeptides') to capture their
prey. Many of these peptides also target mammalian receptors, often with exquisite selectivity. …

ω-Conotoxins selective for N-type calcium channels are useful in the management of severe
pain. In an attempt to expand the therapeutic potential of this class, four new ω-conotoxins (…

Kalata B1 is a member of a new family of polypeptides, isolated from plants, which have a
cystine knot structure embedded within an amide-cyclized backbone. This family of molecules …

Cone snails produce highly complex venom comprising mostly small biologically active
peptides known as conotoxins or conopeptides. Early estimates that suggested 50–200 venom …

The venom of the marine predatory cone snails (genus Conus) has evolved for prey capture
and defense, providing the basis for survival and rapid diversification of the now estimated …

Cnidarians are the oldest extant lineage of venomous animals. Despite their simple anatomy,
they are capable of subduing or repelling prey and predator species that are far more …