… for 2 min with 0.1% (v/v) Nonidet P-40. All solutions used subsequently contained 0.1% Brij
58 (… of the peptide will be published elsewhere (P. Henklein et al., manuscript in preparation). …

… Having identified the part of importin-a which is necessary and sufficient to bind importin-P,
we wanted to know how a heterologous protein to which this domain is fused behaves in an …

In higher eukaryotic cells, the p53 protein is degraded by the ubiquitin–26S proteasome
system mediated by Mdm2 or the human papilloma virus E6 protein. Here we show that COP9 …

The human immunodeficiency virus (HIV) Tat protein is acetylated by the transcriptional
coactivator p300, a necessary step in Tat-mediated transactivation. We report here that Tat is …

Among the currently most popular peptide coupling reagents are the phosphonium [1, 2](BOP,
PyBOP, etc.) and guanidinium [3](HBTU, HATU, etc.) salts. When first described in 1978, …

… Electry,spray mass spectrometry was performed on a triple stage quadrop, le mass spectrometer
TSQ 700 (Finnigan MAT, Bremen, Germany) w th an electrospray (API) ion source. The …

… The peptides Tet008 and Tet009 were clearly able to decrease the luminescence of P.
aeruginosa, with only limited reduction of luminescence upon incubation with the inactive control …

We have identified a conserved region in the C-terminal domain of bromodomain-containing
protein 4 (BRD4) that mediates its specific interaction with positive transcription elongation …

… used in these experiments, the inhibitors were active in human DCs, as ALLM and E64
inhibited fluorogenic calpain substrate II digestion, and bestatin inhibited l-leucine p-nitroanilide …

The COP9 signalosome (CSN) purified from human erythrocytes possesses kinase activity
that phosphoryl ates proteins such as c‐Jun and p53 with consequence for their ubiquitin (Ub)…