Induction of cardiac fibrosis by transforming growth factor-β1

PJ Lijnen, VV Petrov, RH Fagard - Molecular genetics and metabolism, 2000 - Elsevier
The role of transforming growth factor-β 1 (TGF-β 1 ) in the production and deposition of
collagens and in the induction of gene expression in the myocardium in relation to the …

Induction of cardiac fibrosis by aldosterone

P Lijnen, V Petrov - Journal of molecular and cellular cardiology, 2000 - Elsevier
… Author links open overlay panel Paul Lijnen f1 , Victor Petrov … P. Lijnen and V. Petrov.
Induction of Cardiac Fibrosis by Aldosterone. …

Mean and range of the ambulatory pressure in normotensive subjects from a meta-analysis of 23 studies

JA Staessen, RH Fagard, PJ Lijnen, L Thijs… - The American journal of …, 1991 - Elsevier
… Broadhurst et a120 found a correlation of -0.37 (p <0.05) between age and the mean
nighttime BP in men, but not in women, whereas in both sexes the correlations between age and …

Renal effects of cadmium body burden of the general population

…, P De Plaen, J Staessen, A Amery, P Lijnen… - The Lancet, 1990 - Elsevier
In a cross-sectional population study to assess whether environmental exposure to cadmium
is associated with renal dysfunction, 1699 subjects aged 20-80 years were studied as a …

Stimulation of Collagen Production by Transforming Growth Factor-β1 During Differentiation of Cardiac Fibroblasts to Myofibroblasts

VV Petrov, RH Fagard, PJ Lijnen - Hypertension, 2002 - Am Heart Assoc
… (r=0.68, P<… , P<0.001) observed after incubation of cultures of fibroblasts with 600 pmol/L
TGF-β 1 for 48 hours is accompanied by a maximal stimulation of α-SMA expression (3.5-fold, P

The influence of menopause on blood pressure

JA Staessen, CJ Bulpitt, R Fagard, P Lijnen… - Hypertension in …, 1994 - Springer
… However, in women with natural and surgical menopause taken together, the slope of
systolic pressure on age was steeper (p< 0.05), and the intercept tended to be lower (p= 0.08) …

Rise in plasma concentration of aldosterone during long-term angiotensin II suppression

J Staessen, P Lijnen, R Fagard… - Journal of …, 1981 - joe.bioscientifica.com
… The plasma concentration of aldosterone decreased initially from 74 to 21 pg/ml ( P < 0·05)
after 1 month of administration of captopril. Thereafter the plasma concentration of …

Mouse strain determines the outcome of wound healing after myocardial infarction

…, HTM Vervoort-Peters, PM Lijnen… - Cardiovascular …, 2009 - academic.oup.com
… A P-value of less than 0.05 was considered to indicate statistical significance. … Kaplan–Meier
analysis demonstrated significant differences in mortality between the five mouse strains (P

Renin-angiotensin system, hypertrophy and gene expression in cardiac myocytes

P Lijnen, V Petrov - Journal of molecular and cellular cardiology, 1999 - Elsevier
In response to humoral and mechanical stimuli, the myocardium adapts to increased work
load through hypertrophy of individual muscle cells. Myocardial hypertrophy is characterized …

Angiotensin II-induced stimulation of collagen secretion and production in cardiac fibroblasts is mediated via angiotensin II subtype 1 receptors

PJ Lijnen, VV Petrov… - Journal of the Renin …, 2001 - journals.sagepub.com
… -collagen secretion (p<0.01) and production (p<0.01). P-186 had no effect on the Ang II-induced
increase in collagen secretion and production. Addition of telmisartan and P-186 did not …