Analysis of the therapeutic functions of novel melanocortin receptor agonists in MC3R-and MC4R-deficient C57BL/6J mice
KG Kumar, GM Sutton, JZ Dong, P Roubert, P Plas… - Peptides, 2009 - Elsevier
… Analysis of the food intake data using repeated measures ANOVA showed a significant effect
of treatment (P < 0.05), and a significant interaction with time (P < 0.05). When assessed as …
of treatment (P < 0.05), and a significant interaction with time (P < 0.05). When assessed as …
[HTML][HTML] Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment
A Olsson, J Nakhlé, A Sundstedt, P Plas… - … for ImmunoTherapy of …, 2015 - Springer
… (*p = 0.029; two-way ANOVA, Error bars indicate sem) and tumor weights (right panel) at the
end of experiment (*p … to total tumor area (* p < 0.05; Mann Whitney, Error bars indicate sem) …
end of experiment (*p … to total tumor area (* p < 0.05; Mann Whitney, Error bars indicate sem) …
Noninferiority of posterior cervical foraminotomy vs anterior cervical discectomy with fusion for procedural success and reduction in arm pain among patients with …
…, MF Reneman, RJM Groen, JMA Kuijlen, P Plas… - Jama …, 2023 - jamanetwork.com
Importance The choice between posterior cervical foraminotomy (posterior surgery) and
anterior cervical discectomy with fusion (anterior surgery) for cervical foraminal radiculopathy …
anterior cervical discectomy with fusion (anterior surgery) for cervical foraminal radiculopathy …
3-Thio-1, 2, 4-triazoles, novel somatostatin sst2/sst5 agonists
…, A Sidhu, P Plas, P Roubert - Bioorganic & medicinal …, 2005 - Elsevier
… Author links open overlay panel Marie-Odile Contour-Galcéra , Alban Sidhu , Pascale Plas ,
Pierre Roubert … Plas, D. Bigg, C. Thurieau … 37, Wiley-Interscience, New York (1981), p. 251 …
Pierre Roubert … Plas, D. Bigg, C. Thurieau … 37, Wiley-Interscience, New York (1981), p. 251 …
[HTML][HTML] Distinct In Vitro Binding Profile of the Somatostatin Receptor Subtype 2 Antagonist [177Lu]Lu-OPS201 Compared to the Agonist [177Lu]Lu-DOTA-TATE
R Mansi, P Plas, G Vauquelin, M Fani - Pharmaceuticals, 2021 - mdpi.com
Treatment of neuroendocrine tumours with the radiolabelled somatostatin receptor subtype
2 (SST 2 ) peptide agonist [ 177 Lu]Lu-DOTA-TATE is effective and well-established. Recent …
2 (SST 2 ) peptide agonist [ 177 Lu]Lu-DOTA-TATE is effective and well-established. Recent …
Identification of Potent Non-Peptide Somatostatin Antagonists with sst3 Selectivity
…, C Moinet, J Lannoy, J Pommier, P Plas… - Journal of medicinal …, 2001 - ACS Publications
… 2) was prepared by conversion of Boc-d-Trp-OMe to the corresponding thioamide 6 using a
saturated methanolic solution of ammonia under pressure followed by treatment with P 2 S 5 …
saturated methanolic solution of ammonia under pressure followed by treatment with P 2 S 5 …
Atrial natriuretic factor in chronic obstructive lung disease with pulmonary hypertension. Physiological correlates and response to peptide infusion.
…, J Piquet, P Plas, P Braquet… - The Journal of …, 1989 - Am Soc Clin Investig
To investigate the physiological role of atrial natriuretic factor (ANF) in patients with hypoxic
pulmonary hypertension secondary to chronic obstructive lung disease (COLD), we infused …
pulmonary hypertension secondary to chronic obstructive lung disease (COLD), we infused …
Novel pharmacological MC4R agonists can efficiently activate mutated MC4R from obese patient with impaired endogenous agonist response
P Roubert, B Dubern, P Plas… - Journal of …, 2010 - joe.bioscientifica.com
Human melanocortin 4 receptor (hMC4R) mutations with in vitro functional effects are
responsible for 0. 5–2. 5% of severe obesity. Designing ligands that are able to counteract this in …
responsible for 0. 5–2. 5% of severe obesity. Designing ligands that are able to counteract this in …
Regulation of atrial natriuretic factor receptors by angiotensin II in rat vascular smooth muscle cells.
…, P Roubert, MO Lonchampt, P Plas, P Braquet - Journal of Biological …, 1988 - Elsevier
… A total absence of competition was observed with 0.1-1 p~ vasoactive substances including
epinephrine, norepinephrine, serotonin, histamine, Arg-vasopressin, platelet-activating factor…
epinephrine, norepinephrine, serotonin, histamine, Arg-vasopressin, platelet-activating factor…
Identification of a novel series of benzimidazoles as potent and selective antagonists of the human melanocortin-4 receptor
…, S Bernetière, J Camara, P Plas, P Roubert - Bioorganic & medicinal …, 2007 - Elsevier
A novel series of benzimidazoles was identified and optimized, leading to the discovery of
potent and selective antagonists of the human melanocortin-4 receptor. In addition …
potent and selective antagonists of the human melanocortin-4 receptor. In addition …