Hormonal regulation of apoptosis in breast cells and tissues

…, A Kazem, HJ Kloosterboer, I Beusman, P Forgez… - Steroids, 2000 - Elsevier
Few studies have referred to the implication of apoptotic processes following hormonal
treatment. No data are available on the effects of progesterone in breast cells. In order to gain …

The key role of Warburg effect in SARS-CoV-2 replication and associated inflammatory response

P Icard, H Lincet, Z Wu, A Coquerel, P Forgez… - Biochimie, 2021 - Elsevier
Current mortality due to the Covid-19 pandemic (approximately 1.2 million by November 2020)
demonstrates the lack of an effective treatment. As replication of many viruses - including …

Glucocorticoid receptor and breast cancer

…, L Communal, N Mourra, A Courtin, P Forgez… - Breast cancer research …, 2011 - Springer
Stress enhances glucocorticoid (GC) synthesis, which alters inflammation and immune
responses, as well as cellular proliferation and apoptosis in a number of tissues. Increasingly, …

Renin-angiotensin system at the heart of COVID-19 pandemic

M Alifano, P Alifano, P Forgez, A Iannelli - Biochimie, 2020 - Elsevier
Significant aspects of COVID-19 pandemic remain obscure. Angiotensin converting enzyme
2 (ACE2), a component of the renin-angiotensin system, whose expression dominates on …

Cisplatin increases PD-L1 expression and optimizes immune check-point blockade in non-small cell lung cancer

…, A Bobbio, P Icard, J Trédaniel, M Alifano, P Forgez - Cancer letters, 2019 - Elsevier
The number of clinical protocols testing combined therapies including immune check-point
inhibitors and platinum salts is currently increasing in lung cancer treatment, however …

Expression of neurotensin and NT1 receptor in human breast cancer: a potential role in tumor progression

…, E Bruyneel, S Attoub, C Gespach, A Gompel, P Forgez - Cancer research, 2006 - AACR
Emerging evidence supports neurotensin as a trophic and antiapoptotic factor, mediating its
control via the high-affinity neurotensin receptor (NT1 receptor) in several human solid …

[HTML][HTML] Neurotensin and its high affinity receptor 1 as a potential pharmacological target in cancer therapy

…, D Martinez-Fong, J Trédaniel, P Forgez - Frontiers in …, 2013 - frontiersin.org
Cancer is a worldwide health problem. Personalized treatment represents a future
advancement for cancer treatment, in part due to the development of targeted therapeutic drugs. …

Neurotensin receptor 1 determines the outcome of non–small cell lung cancer

…, LD Miller, C Gespach, JF Regnard, P Forgez - Clinical Cancer …, 2010 - AACR
Purpose: This study aimed to investigate the role of the neurotensin/neurotensin receptor I (NTSR1)
complex in non–small cell lung cancer (NSCLC) progression. Experimental Design: …

[PDF][PDF] Lipid transport systems: some recent aspects in swine, cattle and trout during development

MJ Chapman, P Forgez - Reproduction Nutrition …, 1985 - rnd.edpsciences.org
Lipids such as triacylglycerols, free and esterified cholesterol and phospholipids are essentially
insoluble in water; lipoproteins, which are complex macromolecules of pseudomicellar …

[HTML][HTML] The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression

…, A Lavaur, D Hugol, C Gespach, A Gompel, P Forgez - PloS one, 2009 - journals.plos.org
Background The neurotensin (NTS) and its specific high affinity G protein coupled receptor,
the NT1 receptor (NTSR1), are considered to be a good candidate for one of the factors …