Fibroblast growth factor receptor 3 alterations and response to immune checkpoint inhibition in metastatic urothelial cancer: a real world experience

…, WH Weir, GM Mayhew, Y Shibata, P Eulitt… - British journal of …, 2021 - nature.com
Background FGFR3-altered urothelial cancer (UC) correlates with a non-T cell-inflamed
phenotype and has therefore been postulated to be less responsive to immune checkpoint …

Diagnostic nerve ultrasound in Charcot–Marie–Tooth disease type 1B

MS Cartwright, ME Brown, P Eulitt, FO Walker… - Muscle & …, 2009 - Wiley Online Library
Ultrasound is emerging as a useful tool for evaluation of neuromuscular conditions, because
it can provide high‐resolution anatomic information to complement electrodiagnostic data. …

Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells

…, HA Hamed, Y Tang, N Cruickshanks, P Eulitt… - Cancer research, 2011 - AACR
Pemetrexed (ALIMTA, Lilly) is a folate antimetabolite that has been approved by the US
Food and Drug Administration for the treatment of non–small cell lung cancer and has been …

Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo

…, A Pandya Martin, MD Bareford, PJ Eulitt… - Cancer biology & …, 2010 - Taylor & Francis
The present studies have examined approaches to suppress MCL-1 function in breast cancer
cells, as a means to promote tumor cell death. Treatment of breast cancer cells with CDK …

OSU-03012 enhances Ad. 7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins

HA Hamed, A Yacoub, MA Park, PJ Eulitt… - Cancer biology & …, 2010 - Taylor & Francis
The present studies focused on determining whether the autophagy-inducing drug OSU-03012
(AR-12) could enhance the toxicity of recombinant adenoviral delivery of melanoma …

Poly (ADP-ribose) polymerase 1 modulates the lethality of CHK1 inhibitors in carcinoma cells

C Mitchell, M Park, P Eulitt, C Yang, A Yacoub… - Molecular …, 2010 - ASPET
Prior studies have demonstrated that inhibition of CHK1 can promote the activation of extracellular
signal-regulated kinases 1 and 2 (ERK1/2) and phosphorylation of histone H2AX and …

[HTML][HTML] Inhibition of multiple protective signaling pathways and Ad. 5/3 delivery enhances mda-7/IL-24 therapy of malignant glioma

HA Hamed, A Yacoub, MA Park, PJ Eulitt, R Dash… - Molecular Therapy, 2010 - cell.com
We have explored the mechanism by which inhibition of multiple cytoprotective cell-signaling
pathways enhance melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-…

Influence of atrial function and mechanical synchrony on LV hemodynamic status in heart failure patients on resynchronization therapy

…, KC Chang, RD Berger, K Agarwal, P Eulitt… - JACC: Cardiovascular …, 2011 - jacc.org
Objectives : The aim of this study was to evaluate atrial and ventricular function in patients
undergoing cardiac resynchronization therapy (CRT). Background : Right atrial pacing (AP) in …

Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery

PJ Eulitt, MA Park, H Hossein… - Cancer biology & …, 2010 - Taylor & Francis
We have determined whether an adenovirus that comprises the tail and shaft domains of a
serotype 5 virus and the knob domain of a serotype 3 virus expressing MDA-7/IL-24, Ad.5/3-…

Pilot study of [18F] fluorodeoxyglucose positron emission tomography (FDG-PET)/magnetic resonance imaging (MRI) for staging of muscle-invasive bladder cancer …

PJ Eulitt, E Altun, A Sheikh, TZ Wong, ME Woods… - Clinical genitourinary …, 2020 - Elsevier
Introduction Computed tomography (CT) has limited diagnostic accuracy for staging of
muscle-invasive bladder cancer (MIBC). [ 18 F] Fluorodeoxyglucose positron emission …