Derivation and validation of a mathematical model for predicting the response to exogenous recombinant human growth hormone (GH) in prepubertal children with …
MB Ranke, A Lindberg, P Chatelain… - The Journal of …, 1999 - academic.oup.com
Postmarketing surveillance studies of recombinant human GH therapy, such as the Kabi
Pharmacia International Growth Study (KIGS; Pharmacia & Upjohn, Inc., International Growth …
Pharmacia International Growth Study (KIGS; Pharmacia & Upjohn, Inc., International Growth …
Incidence of diabetes mellitus and impaired glucose tolerance in children and adolescents receiving growth-hormone treatment
…, H Bennmarker, K Albertsson-Wikland, P Chatelain… - The Lancet, 2000 - thelancet.com
Background Growth hormone (GH) contributes to insulin resistance, but whether children
treated with GH are at increased risk of diabetes has not been established. We undertook a …
treated with GH are at increased risk of diabetes has not been established. We undertook a …
Evaluation of gonadal function in 107 intersex patients by means of serum antimullerian hormone measurement
…, A Gompel, P Czernichow, P Chatelain… - The Journal of …, 1999 - academic.oup.com
Fetal male sexual differentiation is driven by two testicular hormones: testosterone (synthesized
by interstitial Leydig cells) and antimüllerian hormone (AMH; produced by Sertoli cells …
by interstitial Leydig cells) and antimüllerian hormone (AMH; produced by Sertoli cells …
Binding characteristics of cetirizine and levocetirizine to human H1 histamine receptors: Contribution of Lys191and Thr194
…, N Moguilevsky, R Massingham, P Chatelain - Molecular …, 2002 - ASPET
Competition experiments with [ 3 H]mepyramine showed that cetirizine and its enantiomers,
levocetirizine and (S)-cetirizine, bound with high affinity and stereoselectivity to human H 1 …
levocetirizine and (S)-cetirizine, bound with high affinity and stereoselectivity to human H 1 …
Evidence of a specific complex between adriamycin and negatively-charged phospholipids
E Goormaghtigh, P Chatelain, J Caspers… - … et Biophysica Acta (BBA …, 1980 - Elsevier
Membrane-model systems (monolayers, small unilamellar vesicles) were used to study the
interaction between adriamycin (ADM) and phospholipids. Adsorption of 3 H-labeled …
interaction between adriamycin (ADM) and phospholipids. Adsorption of 3 H-labeled …
Evidence of a complex between adriamycin derivatives and cardiolipin: possible role in cardiotoxicity
E Goormaghtigh, P Chatelain, J Caspers… - Biochemical …, 1980 - Elsevier
Most of the mitochondrial damage induced by antimitotic drugs of the adriamycin family could
be due to the high affinity of these drugs for the membrane. The prime interaction between …
be due to the high affinity of these drugs for the membrane. The prime interaction between …
Binding characteristics of levetiracetam to synaptic vesicle protein 2A (SV2A) in human brain and in CHO cells expressing the human recombinant protein
M Gillard, P Chatelain, B Fuks - European journal of pharmacology, 2006 - Elsevier
A specific binding site for the antiepileptic drug levetiracetam (2S-(oxo-1-pyrrolidinyl)butanamide,
Keppra®) in rat brain, referred to as the levetiracetam binding site, was discovered …
Keppra®) in rat brain, referred to as the levetiracetam binding site, was discovered …
Congenital idiopathic growth hormone deficiency associated with prenatal and early postnatal growth failure
…, AJ Gunn, A Wray, WS Cutfield, PG Chatelain… - The Journal of …, 1992 - Elsevier
To assess the role of growth hormone in fetal and infant growth, we analyzed the pretreatment
data on 52 patients with a diagnosis of congenital growth hormone deficiency before 2 …
data on 52 patients with a diagnosis of congenital growth hormone deficiency before 2 …
Improvement in adult height after growth hormone treatment in adolescents with short stature born small for gestational age: results of a randomized controlled study
JC Carel, P Chatelain, P Rochiccioli… - The Journal of …, 2003 - academic.oup.com
The efficacy of GH for increasing adult height (AH) in short adolescents born small for
gestational age (SGA) is unclear, due to the lack of long-term controlled trials. A total of 168 short …
gestational age (SGA) is unclear, due to the lack of long-term controlled trials. A total of 168 short …
Growth hormone treatment of short children born small for gestational age: growth responses with continuous and discontinuous regimens over 6 years
…, HA Wollmann, P Chatelain… - The Journal of …, 2000 - academic.oup.com
We report an epi-analysis of 6-yr growth responses obtained with GH treatment in short children
born small for gestational age (SGA). Four randomized, multicenter studies explored the …
born small for gestational age (SGA). Four randomized, multicenter studies explored the …