New methods for the synthesis of glycosides and oligosaccharides—are there alternatives to the Koenigs‐Knorr method?[New synthetic methods (56)]
RR Schmidt - Angewandte Chemie International Edition in …, 1986 - Wiley Online Library
Glycoproteins, glycolipids, and glycophospholipids (glycoconjugates) are components of
membranes. The oligosaccharide residue is responsible for intercellular recognition and …
membranes. The oligosaccharide residue is responsible for intercellular recognition and …
Synthetic Lipoteichoic Acid from Staphylococcus aureus Is a Potent Stimulus of Cytokine Release
…, A Stadelmaier, A Geyer, RR Schmidt… - The Journal of …, 2002 - rupress.org
We recently purified lipoteichoic acid (LTA) from Staphylococcus aureus to more than 99%
purity by a novel preparation method and deduced its structure with the first nuclear magnetic …
purity by a novel preparation method and deduced its structure with the first nuclear magnetic …
New principles for glycoside‐bond formation
X Zhu, RR Schmidt - Angewandte Chemie International Edition, 2009 - Wiley Online Library
… Beside the solvent, the nature of the counteranion in the catalyst has a major influence on
the stereoselectivity of Schmidt glycosidation (see Table 3, entries 1–4 for the formation of 74). …
the stereoselectivity of Schmidt glycosidation (see Table 3, entries 1–4 for the formation of 74). …
The crystal structure of human CD1d with and without α-galactosylceramide
The glycolipid α-galactosylceramide binds with high affinity to CD1d and stimulates natural
killer T cells. Here we report the crystal structure of human CD1d in complex with synthetic α-…
killer T cells. Here we report the crystal structure of human CD1d in complex with synthetic α-…
Synthetic routes to thiooligosaccharides and thioglycopeptides
K Pachamuthu, RR Schmidt - Chemical reviews, 2006 - ACS Publications
The ongoing ability of bacteria to resist current antibiotic treatments highlights the need for
alternative strategies for inhibiting their pathogenicity. For many pathogens, including bacteria…
alternative strategies for inhibiting their pathogenicity. For many pathogens, including bacteria…
Hetero-Diels-Alder reaction in highly functionalized natural product synthesis
RR Schmidt - Accounts of Chemical Research, 1986 - ACS Publications
Functionally substituted dihydro-and tetrahydrofuran and-pyran structures play an important
role as intermediates in syntheses of highly functionalized natural products. They are not …
role as intermediates in syntheses of highly functionalized natural products. They are not …
[HTML][HTML] Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell–mediated immunotherapy
…, M Salio, B Mathew, RR Schmidt… - The Journal of …, 2004 - Am Soc Clin Investig
Activation of invariant CD1d-dependent NK T cells (iNKT cells) in vivo through administration
of the glycolipid ligand α-galactosylceramide (α-GalCer) or the sphingosine-truncated α-…
of the glycolipid ligand α-galactosylceramide (α-GalCer) or the sphingosine-truncated α-…
[PDF][PDF] Facile synthesis of a-and P-0-Glycosyl imidates preparation of glycosides and disaccharides
RR Schmidt, J Michel - Angew. Chem. Inr. Ed. Engl, 1980 - thevespiary.org
Glycosides and saccharides are largely synthesized via haloses and their activation by
heavy metal salts-especially silver saltsI'-21. The disadvantages of this method are self-evident. …
heavy metal salts-especially silver saltsI'-21. The disadvantages of this method are self-evident. …
[HTML][HTML] Commensal bacteria regulate Toll-like receptor 3–dependent inflammation after skin injury
…, Y Yang, AL Cogen, ZR Wu, LV Hooper, RR Schmidt… - Nature medicine, 2009 - nature.com
The normal microflora of the skin includes staphylococcal species that will induce inflammation
when present below the dermis but are tolerated on the epidermal surface without …
when present below the dermis but are tolerated on the epidermal surface without …
Glycosylation with highly reactive glycosyl donors: efficiency of the inverse procedure
RR Schmidt, A Toepfer - Tetrahedron letters, 1991 - Elsevier
α-Fucosylation with the reactive trichloroacetimidate 1 as donor and disaccharides 2 and 4
as acceptors led to a remarkable increase in yield under “inverse conditions”, ie addition of …
as acceptors led to a remarkable increase in yield under “inverse conditions”, ie addition of …