[HTML][HTML] Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY

…, D Johnson, MA Statnick, RA Gadski… - Journal of Biological …, 1995 - ASBMB
Neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP) are structurally
related peptides found in all higher vertebrates. NPY is expressed exclusively in neurons, …

Decreased expression of apM1 in omental and subcutaneous adipose tissue of humans with type 2 diabetes

…, TM Suter, JP Sluka, E Ravussin, RA Gadski… - Journal of Diabetes …, 2000 - hindawi.com
We have screened a subtracted cDNA library in order to identify differentially expressed
genes in omental adipose tissue of human patients with Type 2 diabetes. One clone (#1738) …

Molecular cloning and characterization of a human adenocarcinoma/epithelial cell surface antigen complementary DNA

…, JR Sportsman, TF Bumol, JD Sharp, RA Gadski - Cancer research, 1989 - AACR
RA, and Walker, LE Antigens associated with a human lung adenocarcinoma defined …
Young, RA, and Davis, RW Efficient isolation of genes by using antibody probes. Proc. Nati. …

Expression cloning of a human brain neuropeptide Y Y2 receptor.

…, SL Gackenheimer, DA Schober, RA Gadski - Molecular …, 1996 - ASPET
The 36-amino acid peptide, neuropeptide Y (NPY), is a member of a peptide family that
includes the endocrine peptides, peptide YY (PYY), and pancreatic polypeptide (PP). NPY …

Intracellular binding site for a positive allosteric modulator of the dopamine D1 receptor

X Wang, BA Heinz, YW Qian, JH Carter, RA Gadski… - Molecular …, 2018 - ASPET
… in this study (Supplemental Table 2), RA is equivalent to the initial slope of the CRC … RA
(Ehlert, 2005), defined in our study as RA of the mutant construct as a percentage of the RA

Synthesis and SAR of novel histamine H3 receptor antagonists

…, CW Lindsley, FC Stevens, RA Gadski… - Bioorganic & medicinal …, 2006 - Elsevier
The synthesis and biological evaluation of novel tetrahydroisoquinoline, tetrahydroquinoline,
and tetrahydroazepine antagonists of the human and rat H 3 receptors are described. The …

Structure-activity relationships of β-MSH derived melanocortin-4 receptor peptide agonists

…, HM Hsiung, ML Heiman, RA Gadski… - Current Topics in …, 2007 - ingentaconnect.com
The recent emergence of obesity as a major health threat in the industrialized world has
intensified the search for novel and effective pharmacologic treatment. The proopiomelanocortin …

Identification of novel genes differentially expressed in omental fat of obese subjects and obese type 2 diabetic patients

H Corominola, LJ Conner, LS Beavers, RA Gadski… - Diabetes, 2001 - Am Diabetes Assoc
Obesity is associated with an increased risk for developing type 2 diabetes, insulin resistance,
hypertension, dyslipidemia, cardiovascular disease, respiratory dysfunction, and certain …

Discovery of a β-MSH-derived MC-4R selective agonist

…, DP Smith, XY Zhang, RA Gadski… - Journal of medicinal …, 2005 - ACS Publications
A series of novel, disulfide-constrained human β-melanocyte stimulating hormone (β-MSH)-derived
peptides were optimized for in vitro melanocortin-4 receptor (MC-4R) binding affinity, …

In Vivo Selection of Human Tumor Cells Resistant to Monoclonal Antibody-Vinca Alkaloid Immunoconjugates

…, NA Hinson, J Hoskins, BC Laguzza, RA Gadski… - Cancer research, 1990 - AACR
UCLA-P3 human lung adenocarcinoma cells were grown in nude mice and given repetitive
treatments of a monoclonal antibody-Vinca alkaloid immunoconjugate. Although this therapy …