It is well known that females show a greater susceptibility to alcohol-induced liver injury than
males. Additionally, females who consume alcohol regularly and have been obese for 10 …

▪ Abstract Preservation injury remains an obstacle to greater utilization of liver transplantation
therapy. Livers can be preserved a maximum of 24 h in University of Wisconsin solution. …

Considerable evidence for a role of Kupffer cells in alcoholic liver disease has accumulated
and they have recently been shown to be a predominant source of free radicals. Several …

Background & Aims: Tumor necrosis factor (TNF)-α is associated with increased mortality in
alcoholics, but its role in early alcohol-induced liver injury is not fully understood. Recently, it …

… Bradford BU, Misra UK, Thurman RG. Kupffer cells are … Ji S, Lemasters JJ, Thurman RG.
Intralobular hepatic pyridine … Yuki T, Thurman RG. The swift increase in alcohol metabolism. …

… Ji S, Lemasters JJ, Christenson VR, Thurman RG. Periportd and pericentral pyridine
nucleotide fluorescence from the surface of the perfused liver. Evaluation of the hypothesis that …

Microsomes from rat liver form hydrogen peroxide in the presence of an NADPH‐generating
system in proportion to protein concentrations as determined by three independent methods…

In North America, liver disease due to alcohol consumption is an important cause of death
in adults, although its pathogenesis remains obscure. Despite the fact that resident hepatic …

… Thurman RG. Free radical adducts in the bile of rats treated … Bradford BU, Misra UK, Thurman
RG. Kupffer cells are required for sion in … Qu W, Zhong Z, Goto M, Thurman RG. Kupffer cell …

… Iimuro Y, Frankenberg Mv, Arteel GE, Bradford BU, Wall CA, Thurman RG. Female rats
exhibit greater susceptibility to early alcohol-induced injury than males. Am J Physiol 1997;272:…