Rationale This review provides insight for the judicious selection of nicotine dose ranges and
routes of administration for in vivo studies. The literature is replete with reports in which a …

Nicotinic acetylcholine receptors (nACh receptors2) in jawed vertebrates are prototypical
members of the multisubunit, neurotransmitter-gated superfamily of ion channels (ionotropic …

While the monoamine deficiency hypothesis of depression is still most commonly used to
explain the actions of antidepressant drugs, a growing body of evidence has accumulated that …

Nicotinic acetylcholine receptors (nAChR) are diverse members of the neurotransmitter-gated
ion channel superfamily and play critical roles in chemical signaling throughout the …

Nicotinic acetylcholine receptors (nAChRs) containing α7 subunits are thought to assemble
as homomers. α7-nAChR function has been implicated in learning and memory, and …

We determined the levels of endothelial inflammation using MECA‐32 antibody and a4
nicotinic receptor subunit densities employing [ 3 H]epibatidine binding in the brains of …

Bupropion is an atypical antidepressant that also has usefulness as a smoking-cessation aid.
Because hydroxybupropion, a major metabolite of bupropion, is believed to contribute to …

Recent advances concerning effects of chronic nicotine exposure on nicotinic acetylcholine
receptor (nAChR) expression are reviewed. Implications are assessed of these findings for …

Nicotinic acetylcholine receptors (nAChRs) warrant attention, as they play many critical
roles in brain and body function and have been implicated in a number of neurological and …

… of PC12 cell nAChR, is insensitive to blockade by Bgt at concentrations as high as 1 ,uM (49)
but is sensitive to blockade by neosurugatoxin at nanomolar concentrations (Lukas and …