[HTML][HTML] Non-interferometric photoacoustic remote sensing microscopy
Elasto-optical refractive index modulation due to photoacoustic initial pressure transients
produced significant reflection of a probe beam when the absorbing interface had an …
produced significant reflection of a probe beam when the absorbing interface had an …
Porphyrin nanodroplets: Sub‐micrometer ultrasound and photoacoustic contrast imaging agents
A novel class of all‐organic nanoscale porphyrin nanodroplet agents is presented which is
suitable for multimodality ultrasound and photoacoustic molecular imaging. Previous …
suitable for multimodality ultrasound and photoacoustic molecular imaging. Previous …
[HTML][HTML] Multi-wavelength photoacoustic imaging of inducible tyrosinase reporter gene expression in xenograft tumors
RJ Paproski, A Heinmiller, K Wachowicz, RJ Zemp - Scientific reports, 2014 - nature.com
Photoacoustic imaging is an emerging hybrid imaging technology capable of breaking
through resolution limits of pure optical imaging technologies imposed by optical-scattering to …
through resolution limits of pure optical imaging technologies imposed by optical-scattering to …
Tyrosinase as a dual reporter gene for both photoacoustic and magnetic resonance imaging
RJ Paproski, AE Forbrich, K Wachowicz… - Biomedical optics …, 2011 - opg.optica.org
Reporter genes are useful scientific tools for analyzing promoter activity, transfection
efficiency, and cell migration. The current study has validated the use of tyrosinase (involved in …
efficiency, and cell migration. The current study has validated the use of tyrosinase (involved in …
Detection of circulating tumor cells using targeted surface-enhanced Raman scattering nanoparticles and magnetic enrichment
While more than 90% of cancer deaths are due to metastases, our ability to detect circulating
tumor cells (CTCs) is limited by low numbers of these cells in the blood and factors …
tumor cells (CTCs) is limited by low numbers of these cells in the blood and factors …
The role of human nucleoside transporters in uptake of 3′-deoxy-3′-fluorothymidine
RJ Paproski, AML Ng, SYM Yao, K Graham… - Molecular …, 2008 - ASPET
3′-Deoxy-3′-fluorothymidine (FLT) is a positron emission tomography (PET) tracer used
to identify proliferating tumor cells. The purpose of this study was to characterize FLT …
to identify proliferating tumor cells. The purpose of this study was to characterize FLT …
[HTML][HTML] Human concentrative nucleoside transporter 3 transfection with ultrasound and microbubbles in nucleoside transport deficient HEK293 cells greatly increases …
RJ Paproski, SYM Yao, N Favis, D Evans, JD Young… - PloS one, 2013 - journals.plos.org
Gemcitabine is a hydrophilic clinical anticancer drug that requires nucleoside transporters
to cross plasma membranes and enter cells. Pancreatic adenocarcinomas with low levels of …
to cross plasma membranes and enter cells. Pancreatic adenocarcinomas with low levels of …
Biodistribution and uptake of 3′-deoxy-3′-fluorothymidine in ENT1-knockout mice and in an ENT1-knockdown tumor model
RJ Paproski, M Wuest, HS Jans… - Journal of Nuclear …, 2010 - Soc Nuclear Med
18 F-3′-Deoxy-3′-fluorothymidine ( 18 F-FLT) is a PET tracer that accumulates in
proliferating tissues. The current study was undertaken to determine whether equilibrative …
proliferating tissues. The current study was undertaken to determine whether equilibrative …
Enhanced detection of cancer biomarkers in blood-borne extracellular vesicles using nanodroplets and focused ultrasound
The feasibility of personalized medicine approaches will be greatly improved by the
development of noninvasive methods to interrogate tumor biology. Extracellular vesicles shed by …
development of noninvasive methods to interrogate tumor biology. Extracellular vesicles shed by …
[HTML][HTML] Quantitative in vivo whole genome motility screen reveals novel therapeutic targets to block cancer metastasis
K Stoletov, L Willetts, RJ Paproski, DJ Bond… - Nature …, 2018 - nature.com
Metastasis is the most lethal aspect of cancer, yet current therapeutic strategies do not target
its key rate-limiting steps. We have previously shown that the entry of cancer cells into the …
its key rate-limiting steps. We have previously shown that the entry of cancer cells into the …