Apoptotic cell death induced by c-myc is inhibited by bcl-2
RP Bissonnette, F Echeverri, A Mahboubi, DR Green - Nature, 1992 - nature.com
APOPTOSIS is a form of physiological cell death, characterized by chromatin condensation,
cytoplasmic blebbing and DNA fragmentation 1 , which often depends on RNA and protein …
cytoplasmic blebbing and DNA fragmentation 1 , which often depends on RNA and protein …
Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas
Y Shi, JM Glynn, LJ Guilbert, TG Cotter, RP Bissonnette… - Science, 1992 - science.org
Immature T cells and some T cell hybridomas undergo apoptotic cell death when activated
through the T cell receptor complex, a phenomenon that is probably related to antigen …
through the T cell receptor complex, a phenomenon that is probably related to antigen …
The end of the (cell) line: methods for the study of apoptosis in vitro
AJ McGahon, SJ Martin, RP Bissonnette… - Methods in cell …, 1995 - Elsevier
Publisher Summary This chapter describes techniques commonly used to study cell death
using in vitro cell culture systems. These techniques include a range of simple dye exclusion …
using in vitro cell culture systems. These techniques include a range of simple dye exclusion …
[PDF][PDF] Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1, 25-dihydroxyvitamin D3
…, ED Bischoff, L Mere, DE Mais, RP Bissonnette… - Chemistry & biology, 1999 - cell.com
Background: The secosteroid 1,25-dihydroxyvitamin D 3 (1,25(OH) 2 D 3 ) actsthrough the
vitamin D receptor (VDR) to elicit many activities that make it a promising drug candidate for …
vitamin D receptor (VDR) to elicit many activities that make it a promising drug candidate for …
[HTML][HTML] Retinoids cause apoptosis in pancreatic cancer cells via activation of RAR-γ and altered expression of Bcl-2/Bax
F Pettersson, AG Dalgleish, RP Bissonnette… - British journal of …, 2002 - nature.com
All-trans-retinoic acid and 9-cis-retinoic acid have been reported to have inhibitory effects on
pancreatic adenocarcinoma cells and we have shown that this is partly due to induction of …
pancreatic adenocarcinoma cells and we have shown that this is partly due to induction of …
In vivo administration of monoclonal antibodies to the CD3 T cell receptor complex induces cell death (apoptosis) in immature thymocytes.
YF Shi, RP Bissonnette, N Parfrey… - … (Baltimore, Md.: 1950 …, 1991 - journals.aai.org
Some thymocytes, upon activation via the TCR complex in vitro, undergo apoptotic cell death.
In this report, we examine the cell death induced in the thymus after administration of anti-…
In this report, we examine the cell death induced in the thymus after administration of anti-…
A Selective retinoid X receptor agonist bexarotene (targretin) prevents and overcomes acquired paclitaxel (Taxol) resistance in human non–small cell lung cancer
…, RY Prudente, TA Cooke, RP Bissonnette… - Clinical cancer …, 2004 - AACR
Purpose: Paclitaxel is an important anticancer agent for the treatment of non–small cell lung
cancer (NSCLC). However, its use in cancer therapy is limited by development of acquired …
cancer (NSCLC). However, its use in cancer therapy is limited by development of acquired …
Differentiation and growth inhibition mediated via the RXR: PPARγ heterodimer in colon cancer
RM Cesario, J Stone, WC Yen, RP Bissonnette… - Cancer letters, 2006 - Elsevier
This study evaluated the anti-tumor efficacy of combining the RXR agonist, bexarotene, with
the PPARγ agonist, rosiglitazone, in colon cancer. Moser, a human colon cancer cell line, …
the PPARγ agonist, rosiglitazone, in colon cancer. Moser, a human colon cancer cell line, …
Retinoid-X receptor signalling in the developing spinal cord
…, CB Johansson, RH Zetterström, RP Bissonnette… - Nature, 1998 - nature.com
Retinoids regulate gene expression through the action of retinoic acid receptors (RARs) and
retinoid-X receptors (RXRs), which both belong to the family of nuclear hormone receptors …
retinoid-X receptors (RXRs), which both belong to the family of nuclear hormone receptors …
9-cis retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of fas ligand and requires retinoic acid receptor and retinoid X receptor …
RP Bissonnette, T Brunner, SB Lazarchik… - … and cellular biology, 1995 - Am Soc Microbiol
T-cell hybridomas, thymocytes, and T cells can be induced to undergo apoptotic cell death by
activation through the T-cell receptor. This process requires macromolecular synthesis and …
activation through the T-cell receptor. This process requires macromolecular synthesis and …