Clinical pharmacokinetics of the retinoids

RW Lucek, WA Colburn - Clinical pharmacokinetics, 1985 - Springer
Etretinate, isotretinoin (13-cis-retinoic acid), and tretinoin (all-trans-retinoic acid) are retinoic
acid analogues comprising a group of compounds known as the retinoids. However, they …

The role of substituents in the hydrophobic binding of the 1, 4-benzodiazepines by human plasma proteins

RW LUCEK, CB COUTINHO - Molecular Pharmacology, 1976 - ASPET
The effect on the extent of plasma protein binding by varying the substituents on the basic
benzodiazepine molecule has been studied. Hansch lipophilic substituent constants were …

Pharmacokinetics of 14C‐etretinate in healthy volunteers and two patients with biliary t‐tube drainage

RW Lucek, CJL Bugge, T Crews… - … & drug disposition, 1988 - Wiley Online Library
The pharmacokinetic profile of 14 C‐etretinate, a retinoid that is effective in the treatment of
psoriasis, was studied in six healthy male volunteers and two biliary T‐tube patients. …

Noncompartmental area under the curve determinations for drugs that cycle in the bile

WA Colburn, RW Lucek - Biopharmaceutics & drug disposition, 1988 - Wiley Online Library
Drugs that are involved in the enterohepatic circulation (EHC) generally exhibit complex
disposition profiles and are difficult to describe by classical methods. A noncompartmental …

[PDF][PDF] Further studies on medazepam metabolism in the rat

RW Lucek, CB Coutinho, JA Cheripko, J Ryan… - Drug Metabolism and …, 1975 - Citeseer
Previous studies with 9000g supernatant fractions of rat liver revealed that the 1. 4-ben-zodiazepine.
medazepam. was converted to N-desmethyldiazepam by a series of reactions …

[CITATION][C] A new approach to the determination of protein‐bound bilirubin displacement and its applications

CB Coutinho, RW Lucek, JA Cheripko… - Annals of the New …, 1973 - Wiley Online Library
Numerous workers have established that bilirubin binds strongly to plasma protein.'-'; The
extent of this binding depends on the affinity between bilirubin and the plasma protein, the …

[PDF][PDF] Pamięć Tadeusza Kościuszki we Francji:(w 200 rocnicę Insurekcji Kościuszkowskiej)

A Łucka - Notatki Płockie. Kwartalnik Towarzystwa Naukowego …, 1994 - bibliotekanauki.pl
Na południowym skraju Lasku Fontainebleau, nad rzeką Loing-lewobrzeżnym dopływem
Sekwany, jeszcze dzisiaj można zwiedzać pozostałości po KAPLICZCE wzniesionej, by uczcić …

Stanisław Łucki–kochał ojczyznę i walczył o wolność Polski

A Łucka - Studia Polonijne, 2020 - ceeol.com
Atak niemiecki na Polskę we wrześniu 1939 r. i szybki rozwój sytuacji wojskowej z jednej
strony i okupacja sowiecka z drugiej strony powodują przekroczenie granicy węgierskiej, …

[CITATION][C] CNDO-2 MOLECULAR-ORBITAL STUDY OF SELECTED 1, 3-DIHYDRO-5-PHENYL-1, 4-BENZODIAZEPIN-2-ONES

RW Lucek, WA Garland… - FEDERATION …, 1979 - FEDERATION AMER SOC EXP …

[CITATION][C] Pharmacolin., 10 (1985)

RW Lucek, WAC Clin - CrossRef View in Scopus