Nanotechnology in diabetes research has facilitated the development of novel glucose
measurement and insulin delivery modalities which hold the potential to dramatically improve …

… Roberto Di Santo Roberto Di Santo … SAR studies of this lead compound led to the development
of (1R,2S)-2-amino-4-methylene-cyclopentane carboxylic acid (PLD-118, icofungipen, 26…

A glucose-responsive “closed-loop” insulin delivery system mimicking the function of pancreatic
cells has tremendous potential to improve quality of life and health in diabetics. Here, we …

Stimuli-triggered drug delivery systems have been increasingly used to promote physiological
specificity and on-demand therapeutic efficacy of anticancer drugs. Here we utilize …

The HIV-1 genomic RNA reverse transcription is an essential step in the virus cycle carried
out by the viral-coded reverse transcriptase (RT), which has two associated functions: the …

The evolution of a mesophilic aminotransferase, isolated from Athrobacter citreus, to a
thermostable aminotransferase was accomplished via error-prone PCR. After three rounds of …

Various cinnammoyl-based structures were synthesized and tested in enzyme assays as
inhibitors of the HIV-1 integrase (IN). The majority of compounds were designed as …

A number of known antifungal pyrrole derivatives and some newly synthesized compounds (5–33)
were tested in vitro against Mycobacterium tuberculosis CIP 103471. The majority of …

The human immunodeficiency virus-type 1 (HIV-1) reverse transcriptase (RT) is a multifunctional
enzyme which displays DNA polymerase activity, which recognizes RNA and DNA …

Growing attention to environmental protection leads food industries to adopt a model of “circular
economy” applying safe and sustainable technologies to recover, recycle and valorize …