Among the four G protein–coupled receptors (H 1 –H 4 ) identified as mediators of the
biologic effects of histamine, the H 3 receptor (H 3 R) is distinguished for its almost exclusive …

Variants at the GBA locus, encoding glucocerebrosidase, are the strongest common genetic
risk factor for Parkinson's disease (PD). To understand GBA-related disease mechanisms, …

… RH 3 R heteromerization … R heteromers in vivo by co-immunoprecipitation. Finally, we found
that in the same preparation H 3 R activation resulted in decreased binding affinity of A 2A R …

… By using rat GP isolated nerve terminals (synaptosomes), we studied whether H 3 R activation
modified the previously reported enhancing action of adenosine A 2A receptor (A 2A R) …

Essential oils are widely employed in food industry as natural flavors, however, these
compounds are very difficult to handle due to they are very susceptible to oxidation and …

Understanding medium spiny neuron (MSN) physiology is essential to understand motor
impairments in Parkinson’s disease (PD) given the architecture of the basal ganglia. Here, we …

… , and H 3 R activation or D 1 R blockade prevented the effect of … R agonist SKF-81297 (37
ng/1 μl) or the H 3 R agonist RAMH increased Akt phosphorylation, prevented by D 1 R/H 3 R …

A reduction in the synthesis of the neuromodulator histamine has been associated with
Tourette's syndrome and obsessive-compulsive disorder. Symptoms of these disorders are …

Albeit cholinergic depletion remains the key event in Alzheimer’s Disease (AD), recent
information describes stronger links between monoamines (trace amines, catecholamines, …

… MARÍA ISABEL MÁRQUEZ GÓMEZ ROOSE MARY MÁRQUEZ GÓMEZ … Docente María
Isabel Márquez Gómez, Licenciada en Educación Preescolar y promoción a la Familia. …