PD-1-mediated suppression of IL-2 production induces CD8+ T cell anergy in vivo

…, S Terawaki, T Hayashi, R Nabeshima… - The Journal of …, 2009 - journals.aai.org
Accumulating evidence suggests that PD-1, an immuno-inhibitory receptor expressed on
activated T cells, regulates peripheral T cell tolerance. In particular, PD-1 is involved in the …

GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites

…, J Aoki, N Okada, T Kida, M Ishii, R Nabeshima… - Nature, 2019 - nature.com
… -type genomic DNA with PstI generates 5.2-kb DNA fragments in Gpr31a and Gpr31c, and
a 6.6-kb fragment in Gpr31b whereas the digestion of the mutant genomic DNA with a neo R

Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm

F Dong, K Shinohara, Y Botilde, R Nabeshima… - Journal of Cell …, 2014 - rupress.org
Axonemal dynein complexes are preassembled in the cytoplasm before their transport to
cilia, but the mechanism of this process remains unclear. We now show that mice lacking …

Bone marrow stroma from refractory anemia of myelodysplastic syndrome is defective in its ability to support normal CD34-positive cell proliferation and differentiation …

…, M Yaguchi, M Hiramoto, H Hoshi, R Nabeshima… - Leukemia research, 1999 - Elsevier
We examined the supportive function of stromal cells from patients with refractory anemia (RA)
of myelodysplastic syndrome (MDS) on CD34-positive hematopoietic cell proliferation …

Transport of the outer dynein arm complex to cilia requires a cytoplasmic protein Lrrc6

…, Y Botilde, R Nabeshima, K Takaoka, R Ajima… - Genes to …, 2016 - Wiley Online Library
Lrrc6 encodes a cytoplasmic protein that is expressed specifically in cells with motile cilia
including the node, trachea and testes of the mice. A mutation of Lrrc6 has been identified in …

Hematopoietic supportive function of human bone marrow stromal cell lines established by a recombinant SV40-adenovirus vector.

…, T Imai, M Yasuda, R Nabeshima… - Experimental …, 1994 - europepmc.org
We have previously reported the establishment of a variety of human bone marrow stromal
cell lines using a recombinant SV40-adenovirus vector. Using this vector, we obtained more …

Development of an electrically small one-sided directional antenna with matching circuit

H Kanaya, R Nabeshima, R Pokharel… - 2008 IEEE Radio …, 2008 - ieeexplore.ieee.org
We designed an electrically small antenna (ESA) with coplanar waveguide (CPW) matching
circuit. Matching circuit is realized by using interdigital gap and transmission line. Our ESA …

Stimulatory effects of substance P on CD34 positive cell proliferation and differentiation in vitro are mediated by the modulation of stromal cell function.

…, M Hoque, R Nabeshima… - International …, 1998 - spandidos-publications.com
Substance P (SP) is a neuropeptide widely distributed in the nervous system. Extensive study
has shown SP stimulates production of various cytokines by bone marrow stromal cells, …

Loss of Fam60a, a Sin3a subunit, results in embryonic lethality and is associated with aberrant methylation at a subset of gene promoters

R Nabeshima, O Nishimura, T Maeda, N Shimizu, T Ide… - Elife, 2018 - elifesciences.org
10.7554/eLife.36435.001 We have examined the role of Fam60a, a gene highly expressed
in embryonic stem cells, in mouse development. Fam60a interacts with components of the …

[HTML][HTML] Response of patients with acute respiratory failure caused by COVID-19 to awake-prone position outside the intensive care unit based on pulmonary …

…, JDA Umada, APS Alves, RP Nabeshima… - Clinics, 2021 - SciELO Brasil
OBJECTIVES: Since there are difficulties in establishing effective treatments for COVID-19,
a vital way to reduce mortality is an early intervention to prevent disease progression. This …