Interaction of methylenedioxyphenyl (1, 3-benzodioxole) compounds with enzymes and their effects on mammals
E Hodgson, RM Philpot - Drug metabolism reviews, 1975 - Taylor & Francis
… achieved with an in vitro system by Philpot and Hodgson [92]. … [l69] using mouse liver
microsomes and by Philpot and Hodgson … Preliminary experiments by Philpot and Hodgson [92] …
microsomes and by Philpot and Hodgson … Preliminary experiments by Philpot and Hodgson [92] …
Capturing violence in the night-time economy: A review of established and emerging methodologies
Night-time economy (NTE) leisure zones, while providing local economic growth and
positive social experiences, are hotspots for urban public violence. Research aimed at better …
positive social experiences, are hotspots for urban public violence. Research aimed at better …
The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression
RN Hines, JR Cashman, RM Philpot… - Toxicology and applied …, 1994 - Elsevier
The flavin-containing monooxygenase (FMO) has been characterized in several mammalian
species, including human. The FMO forms a stable NADP(H)− and oxygen-dependent 4α-…
species, including human. The FMO forms a stable NADP(H)− and oxygen-dependent 4α-…
Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3
…, C Ibarra, R Gasser, K Itagaki, RM Philpot… - Biochemical …, 1998 - Elsevier
In the present study, we expressed human flavin-containing monooxygenase 1 (FMO1), FMO3,
FMO4t (truncated), and FMO5 in the baculovirus expression vector system at levels of 0.6 …
FMO4t (truncated), and FMO5 in the baculovirus expression vector system at levels of 0.6 …
Characterization of the acute clinical illness associated with human immunodeficiency virus infection
…, D Grant, A Morlet, R Philpot, R Jones… - Archives of internal …, 1988 - jamanetwork.com
• The clinical and serologic features and immune status of 39 homosexual men who had
seroconversion to human immunodeficiency virus positivity were compared with 26 …
seroconversion to human immunodeficiency virus positivity were compared with 26 …
A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities
…, T Kimura, J Ozols, IR Phillips, RM Philpot… - Archives of Biochemistry …, 1994 - Elsevier
… , each species examined by analysis of genomic DNA (rabbits, humans, rats, mice, guinea
pigs, and hamsters) appears to contain the same set of FMO genes (12; Burnett and Philpot, …
pigs, and hamsters) appears to contain the same set of FMO genes (12; Burnett and Philpot, …
Would I be helped? Cross-national CCTV footage shows that intervention is the norm in public conflicts.
Half a century of research on bystander behavior concludes that individuals are less likely
to intervene during an emergency when in the presence of others than when alone. By …
to intervene during an emergency when in the presence of others than when alone. By …
[PDF][PDF] Relationship of cytochrome P450 activity to Clara cell cytotoxicity. IV. Metabolism of naphthalene and naphthalene oxide in microdissected airways from mice …
…, A Weir, L Van Winkle, X Duan, R Philpot… - Molecular …, 1995 - Citeseer
Parenteral administration of naphthalene produces a dosedependent and tissue-, species-,
and cell-selective lesion of munne Clara cells. The rate and stereoselectivity of naphthalene …
and cell-selective lesion of munne Clara cells. The rate and stereoselectivity of naphthalene …
Quantitation and kinetic properties of hepatic microsomal and recombinant flavin-containing monooxygenases 3 and 5 from humans
LH Overby, GC Carver, RM Philpot - Chemico-biological interactions, 1997 - Elsevier
… However, agreement between the rates of metabolism in each sample was excellent (r=0.95),
and each rate was directly proportional to the FMO3 concentration (r=0.99 with …
and each rate was directly proportional to the FMO3 concentration (r=0.99 with …
Place conditioning: age‐related changes in the rewarding and aversive effects of alcohol
RM Philpot, KA Badanich… - Alcoholism: clinical and …, 2003 - Wiley Online Library
Background: Alcohol abuse levels are very high in adolescents, creating a significant societal
issue. It has been shown that people who begin alcohol use as adolescents are more …
issue. It has been shown that people who begin alcohol use as adolescents are more …