Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the Aβ subunit gene
R Ruediger, HT Pham, G Walter - Oncogene, 2001 - nature.com
Protein phosphatase 2A (PP2A) consists of three subunits, A, B and C. The A and B subunits
have regulatory functions while C is the catalytic subunit. PP2A core enzyme is composed …
have regulatory functions while C is the catalytic subunit. PP2A core enzyme is composed …
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the Aα subunit gene
R Ruediger, HT Pham, G Walter - Oncogene, 2001 - nature.com
The A subunit of protein phosphatase 2A (PP2A) consists of 15 nonidentical repeats. The
catalytic C subunit binds to C-terminal repeats 11–15 and regulatory B subunits bind to N-…
catalytic C subunit binds to C-terminal repeats 11–15 and regulatory B subunits bind to N-…
Human cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice
R Ruediger, J Ruiz, G Walter - Molecular and cellular biology, 2011 - Taylor & Francis
Strong evidence has indicated that protein phosphatase 2A (PP2A) is a tumor suppressor,
but a mouse model for testing the tumor suppressor activity was missing. The most abundant …
but a mouse model for testing the tumor suppressor activity was missing. The most abundant …
Characterization of the Aalpha and Abeta subunit isoforms of protein phosphatase 2A: differences in expression, subunit interaction, and evolution
J Zhou, HT Pham, R Ruediger, G Walter - Biochemical Journal, 2003 - portlandpress.com
Protein phosphatase 2A (PP2A) is very versatile owing to a large number of regulatory subunits
and its ability to interact with numerous other proteins. The regulatory A subunit exists as …
and its ability to interact with numerous other proteins. The regulatory A subunit exists as …
Association of protein phosphatase 2A with polyoma virus medium tumor antigen.
G Walter, R Ruediger, C Slaughter… - Proceedings of the …, 1990 - National Acad Sciences
The polyoma virus medium and small tumor antigens, as well as simian virus 40 small
tumor antigen, form specific complexes with two cellular proteins designated 61- and 37-kDa …
tumor antigen, form specific complexes with two cellular proteins designated 61- and 37-kDa …
Identification of binding sites on the regulatory A subunit of protein phosphatase 2A for the catalytic C subunit and for tumor antigens of simian virus 40 and …
R Ruediger, D Ro Eckel, J Fait, A Bergqvist… - … and cellular biology, 1992 - Taylor & Francis
Protein phosphatase 2A is composed of three subunits: the catalytic subunit C and two
regulatory subunits, A and B. The A subunit consists of 15 nonidentical repeats and has a rodlike …
regulatory subunits, A and B. The A subunit consists of 15 nonidentical repeats and has a rodlike …
Molecular model of the A subunit of protein phosphatase 2A: interaction with other subunits and tumor antigens
R Ruediger, M Hentz, J Fait, M Mumby… - Journal of virology, 1994 - Am Soc Microbiol
Protein phosphatase 2A consists of three subunits, the catalytic subunit (C) and two regulatory
subunits (A and B). The A subunit has a rod-like shape and consists of 15 nonidentical …
subunits (A and B). The A subunit has a rod-like shape and consists of 15 nonidentical …
Constant expression and activity of protein phosphatase 2A in synchronized cells
R Ruediger, JEVW Hood, M Mumby… - Molecular and cellular …, 1991 - Am Soc Microbiol
The levels of the A, B, and C subunits of protein phosphatase 2A in extracts from synchronized
embryonic bovine tracheal cells were determined by immunoblotting with subunit-specific …
embryonic bovine tracheal cells were determined by immunoblotting with subunit-specific …
[HTML][HTML] Protein phosphatase 2A holoenzyme assembly: identification of contacts between B-family regulatory and scaffolding A subunits
Protein serine/threonine phosphatase (PP) 2A is a ubiquitous enzyme with pleiotropic
functions. Trimeric PP2A consists of a structural A subunit, a catalytic C subunit, and a variable …
functions. Trimeric PP2A consists of a structural A subunit, a catalytic C subunit, and a variable …
Reduced expression of the Aα subunit of protein phosphatase 2A in human gliomas in the absence of mutations in the Aα and Aβ subunit genes
Protein phosphatase 2A (PP2A) consists of 3 subunits: the catalytic subunit, C, and the
regulatory subunits, A and B. The A and C subunits both exist as 2 isoforms (α and β) and the B …
regulatory subunits, A and B. The A and C subunits both exist as 2 isoforms (α and β) and the B …