Local action on outdoor air pollution to improve public health

S Vardoulakis, R Kettle, P Cosford, P Lincoln… - International journal of …, 2018 - Springer
Objectives The National Institute for Health and Care Excellence, jointly with Public Health
England, have developed a guideline on outdoor air pollution and its links to health. The …

Expression and characterization of a 5-oxo-6E, 8Z, 11Z, 14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils

…, U Bhatia, K Seuwen, P Tranter, J Turner, R Kettle… - Molecular …, 2003 - ASPET
Using a bioinformatics approach, we have isolated a novel G-protein-coupled receptor (GPCR),
R527, and have demonstrated that this receptor shows no significant homology to …

Tuberculosis—diagnosis, management, prevention, and control: summary of updated NICE guidance

LE Hoppe, R Kettle, M Eisenhut, I Abubakar - bmj, 2016 - bmj.com
Lucy Elizabeth Hoppe technical analyst (clinical) 1, Rachel Kettle technical advisor (public
health) 2, Michael Eisenhut consultant paediatrician and member of the Guideline …

Identifying evidence for public health guidance: a comparison of citation searching with Web of Science and Google Scholar

P Levay, N Ainsworth, R Kettle… - Research Synthesis …, 2016 - Wiley Online Library
Aim To examine how effectively forwards citation searching with Web of Science (WOS) or
Google Scholar (GS) identified evidence to support public health guidance published by the …

[HTML][HTML] The multiple antibiotic resistance operon of enteric bacteria controls DNA repair and outer membrane integrity

…, JRJ Haycocks, AD Middlemiss, RA Kettles… - Nature …, 2017 - nature.com
The multiple antibiotic resistance (mar) operon of Escherichia coli is a paradigm for
chromosomally encoded antibiotic resistance in enteric bacteria. The locus is recognised for its …

Regulation of neuregulin 1β1–induced MUC5AC and MUC5B expression in human airway epithelium

R Kettle, J Simmons, F Schindler, P Jones… - American journal of …, 2010 - atsjournals.org
Excessive mucus production has been linked to many of the pathologic features of respiratory
diseases, including obstruction of the airways, decline in lung function, increased rates of …

The Escherichia coli MarA protein regulates the ycgZymgABC operon to inhibit biofilm formation

RA Kettles, N Tschowri, KJ Lyons… - Molecular …, 2019 - Wiley Online Library
The Escherichia coli marRAB operon is a paradigm for chromosomally encoded antibiotic
resistance. The operon exerts its effect via an encoded transcription factor called MarA that …

The Escherichia coli multiple antibiotic resistance activator protein represses transcription of the lac operon

…, S Ahmed, LE Lamberte, RA Kettles… - Biochemical Society …, 2019 - portlandpress.com
In Escherichia coli, the marRAB operon is a determinant for antibiotic resistance. Such
phenotypes require the encoded transcription factor MarA that activates efflux pump expression. …

[HTML][HTML] Improved production and biophysical analysis of recombinant silicatein-α

EI Sparkes, RA Kettles, CS Egedeuzu, NL Stephenson… - Biomolecules, 2020 - mdpi.com
Silicatein-α is a hydrolase found in siliceous sea sponges with a unique ability to condense
and hydrolyse silicon–oxygen bonds. The enzyme is thus of interest from the perspective of …

NICE public health guidance update

M Van Hove, R Kettle, R Walsh, G Leng - 2019 - academic.oup.com
This article covers recent National Institute for Health and Care Excellence guidance
relevant to public health. The article includes an overview of key public health aspects of the …