Cancer chemoprevention by natural products: how far have we come?

RG Mehta, G Murillo, R Naithani, X Peng - Pharmaceutical research, 2010 - Springer
Since ancient times, natural products, herbs and spices have been used for preventing several
diseases, including cancer. The term chemoprevention was coined in the late 1970s and …

Antiviral activity of phytochemicals: a comprehensive review

R Naithani, LC Huma, LE Holland… - Mini reviews in …, 2008 - ingentaconnect.com
Numerous numbers of biologically active agents have been identified for their diverse
therapeutic functions. Detailed investigations of phytochemicals for antiviral activities have …

The reaction between hydrazines and β-dicarbonyl compounds: proposal for a mechanism

SP Singh, D Kumar, H Batra, R Naithani… - Canadian Journal of …, 2000 - cdnsciencepub.com
The reaction between aryl or heteroarylhydrazines with fluorinated β-diketones (CF 3
COCH 2 COR) yields a variety of 3-, 5-, and 3,5-trifluoromethylpyrazoles and 5-trifluoromethyl-5-…

Organoselenium compounds in cancer chemoprevention

R Naithani - Mini reviews in medicinal chemistry, 2008 - ingentaconnect.com
Selenium is an important trace element involved in different physiological functions of human
body. Knowledge of selenium in biology of cancer has increased at rapid rate especially …

Comprehensive review of cancer chemopreventive agents evaluated in experimental carcinogenesis models and clinical trials

R Naithani, LC Huma, RM Moriarty… - Current medicinal …, 2008 - ingentaconnect.com
Cancer chemoprevention refers to the use of pharmacological agents to inhibit, delay or
reverse the multi-step process of carcinogenesis. The last two decades in particular have …

Organosulfur compounds in cancer chemoprevention

RM Moriarty, R Naithani, B Surve - Mini reviews in medicinal …, 2007 - ingentaconnect.com
There has been a renewed interest to the application of natural products derived from
cruciferous plants and members of Allium genus in chemoprevention of cancer. The potential …

Antiviral activity of phytochemicals: a current perspective

R Naithani, RG Mehta, D Shukla… - Dietary components and …, 2010 - Springer
Key Points A wide variety of active phytochemicals have been found to have therapeutic
applications against genetically and functionally diverse viruses. The antiviral mechanism of …

Down-regulation of inhibitor of apoptosis proteins by deguelin selectively induces apoptosis in breast cancer cells

…, P Karna, RM O'Regan, XJ Liu, R Naithani… - Molecular …, 2007 - ASPET
The identification of differentially regulated apoptotic signals in normal and tumor cells allows
the development of cancer cell-selective therapies. Increasing evidence shows that the …

[HTML][HTML] Cell transdifferentiation and reprogramming in disease modeling: insights into the neuronal and cardiac disease models and current translational strategies

RS Kalra, JK Dhanjal, M Das, B Singh, R Naithani - Cells, 2021 - mdpi.com
Cell transdifferentiation and reprogramming approaches in recent times have enabled the
manipulation of cell fate by enrolling exogenous/artificial controls. The chemical/small …

Synthesis of Abyssinone II and related compounds as potential chemopreventive agents

…, SN Chandersekera, O Prakash, R Naithani - European journal of …, 2006 - Elsevier
A facile and efficient approach to the synthesis of prenylated flavonoids as potential
chemopreventive agents has been described. This features the synthesis of prenyl halide, …