Down-regulation does not mediate natriuretic peptide-dependent desensitization of natriuretic peptide receptor (NPR)-A or NPR-B: guanylyl cyclase-linked natriuretic …
D Fan, PM Bryan, LK Antos, RJ Potthast… - Molecular pharmacology, 2005 - ASPET
Natriuretic peptide receptor A (NPR-A/GC-A) and B (NPR-B/GC-B) are members of the
transmembrane guanylyl cyclase family that mediate the effects of natriuretic peptides via the …
transmembrane guanylyl cyclase family that mediate the effects of natriuretic peptides via the …
[CITATION][C] Downregulation does not mediate natriuretic peptide-dependent desensitization of NPR-A or NPR-B: guanylyl cyclase-linked natriuretic peptide receptors …
D Fan, PM Bryan, LK Antos, RJ Potthast… - Molecular …, 2004 - ASPET
Natriuretic peptide receptor A (NPR-A/GC-A) and B (NPR-B/GC-B) are members of the
transmembrane guanylyl cyclase family that mediate the effects of natriuretic peptides via the …
transmembrane guanylyl cyclase family that mediate the effects of natriuretic peptides via the …
Phosphorylation-dependent regulation of the guanylyl cyclase-linked natriuretic peptide receptors
R Potthast, LR Potter - Peptides, 2005 - Elsevier
Natriuretic peptides are a family of hormones/paracrine factors that regulate blood pressure,
cardiovascular homeostasis and bone growth. The mammalian family consists of atrial …
cardiovascular homeostasis and bone growth. The mammalian family consists of atrial …
[HTML][HTML] Calcium-dependent dephosphorylation mediates the hyperosmotic and lysophosphatidic acid-dependent inhibition of natriuretic peptide receptor-B/guanylyl …
R Potthast, SE Abbey-Hosch, LK Antos… - Journal of Biological …, 2004 - ASBMB
C-type natriuretic peptide binding to natriuretic peptide receptor-B (NPR-B) stimulates cGMP
synthesis, which regulates vasorelaxation, cell proliferation, and bone growth. Here, we …
synthesis, which regulates vasorelaxation, cell proliferation, and bone growth. Here, we …
High salt intake increases uroguanylin expression in mouse kidney
R Potthast, E Ehler, LA Scheving, A Sindic… - …, 2001 - academic.oup.com
The intestinal peptides, guanylin and uroguanylin, may have an important role in the endocrine
control of renal function. Both peptides and their receptor, guanylyl cyclase C (GC-C), are …
control of renal function. Both peptides and their receptor, guanylyl cyclase C (GC-C), are …
Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure
…, B Skryabin, M Steinmetz, R Potthast… - Proceedings of the …, 2002 - National Acad Sciences
Atrial natriuretic peptide (ANP) is an important regulator of arterial blood pressure. The
mechanisms mediating its hypotensive effects are complex and involve the inhibition of the …
mechanisms mediating its hypotensive effects are complex and involve the inhibition of the …
[HTML][HTML] Impact of inclusion of industry trial results registries as an information source for systematic reviews
R Potthast, V Vervoelgyi, N McGauran, MF Kerekes… - PLoS …, 2014 - journals.plos.org
Background Clinical trial results registries may contain relevant unpublished information.
Our main aim was to investigate the potential impact of the inclusion of reports from industry …
Our main aim was to investigate the potential impact of the inclusion of reports from industry …
Diverging vasorelaxing effects of C-type natriuretic peptide in renal resistance arteries and aortas of GC-A-deficient mice
M Steinmetz, R Potthast, K Sabrane, M Kuhn - Regulatory peptides, 2004 - Elsevier
This study aimed to characterize the vasorelaxing effects of ANP, BNP and CNP in isolated
renal resistance arteries (RRA) from wild-type mice and mice with either systemic (GC-A −/−) …
renal resistance arteries (RRA) from wild-type mice and mice with either systemic (GC-A −/−) …
Increased effects of C-type natriuretic peptide on cardiac ventricular contractility and relaxation in guanylyl cyclase A-deficient mice
…, SM Lohmann, W Schmitz, R Potthast… - Cardiovascular …, 2002 - academic.oup.com
Objective: The natriuretic peptides (NPs), atrial (ANP), B-type (BNP), and C-type (CNP) natriuretic
peptides as well as their respective receptor-guanylyl cyclases (GC-A for ANP and BNP…
peptides as well as their respective receptor-guanylyl cyclases (GC-A for ANP and BNP…
[HTML][HTML] Guanylin, uroguanylin, and heat-stable euterotoxin activate guanylate cyclase C and/or a pertussis toxin-sensitive G protein in human proximal tubule cells
…, C Başoglu, A Cerçi, JR Hirsch, R Potthast… - Journal of Biological …, 2002 - ASBMB
Membrane guanylate cyclase C (GC-C) is the receptor for guanylin, uroguanylin, and heat-stable
enterotoxin (STa) in the intestine. GC-C-deficient mice show resistance to STa in …
enterotoxin (STa) in the intestine. GC-C-deficient mice show resistance to STa in …