User profiles for Richard B. van Breemen
Richard B van BreemenDirector, Linus Pauling Institute, Oregon State University Verified email at oregonstate.edu Cited by 25938 |
Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms
…, H Xu, C Gu, RB Van Breemen… - Journal of agricultural …, 2001 - ACS Publications
… Bolton, Richard B. van Breemen. Ultrafiltration tandem mass spectrometry of estrogens
for characterization of structure and affinity for human estrogen receptors. Journal of the …
for characterization of structure and affinity for human estrogen receptors. Journal of the …
Caco-2 cell permeability assays to measure drug absorption
RB Van Breemen, Y Li - Expert opinion on drug metabolism & …, 2005 - Taylor & Francis
Caco-2 cells are a human colon epithelial cancer cell line used as a model of human intestinal
absorption of drugs and other compounds. When cultured as a monolayer, Caco-2 cells …
absorption of drugs and other compounds. When cultured as a monolayer, Caco-2 cells …
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2
…, G Liu, JM Pezzuto, RB Van Breemen… - Proceedings of the …, 2005 - National Acad Sciences
The risks of cancer and other degenerative diseases caused by reactive oxygen species
and electrophiles can be reduced by the up-regulation of detoxifying enzymes. A major …
and electrophiles can be reduced by the up-regulation of detoxifying enzymes. A major …
An LC-MS method for analyzing total resveratrol in grape juice, cranberry juice, and in wine
…, Y Yang, R Roderick, RB van Breemen - Journal of agricultural …, 2002 - ACS Publications
Resveratrol is an antioxidant found in grapes, grape products, and some other botanical
sources with antiinflammatory and anticancer properties. In grapes and wine, it occurs both as …
sources with antiinflammatory and anticancer properties. In grapes and wine, it occurs both as …
Human, rat, and mouse metabolism of resveratrol
Purpose. Resveratrol, a phenolic phytoalexin occurring in grapes, wine, peanuts, and
cranberries, has been reported to have anticarcinogenic, antioxidative, phytoestrogenic, and …
cranberries, has been reported to have anticarcinogenic, antioxidative, phytoestrogenic, and …
Cannabinoids block cellular entry of SARS-CoV-2 and the emerging variants
As a complement to vaccines, small-molecule therapeutic agents are needed to treat or
prevent infections by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its …
prevent infections by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its …
Multitargeted therapy of cancer by lycopene
RB Van Breemen, N Pajkovic - Cancer letters, 2008 - Elsevier
Lycopene (ψ,ψ-carotene) is the most abundant carotenoid in tomatoes and is the red pigment
of not only tomatoes but also rosehips, watermelon, papaya, pink grapefruit, and guava. …
of not only tomatoes but also rosehips, watermelon, papaya, pink grapefruit, and guava. …
Modification of keap1 cysteine residues by sulforaphane
…, AD Mesecar, RB Van Breemen - Chemical research in …, 2011 - ACS Publications
Activation of the transcription factor NF-E2-related factor-2 (Nrf2) through modification of
Kelch-like ECH-associated protein 1 (Keap1) cysteines, leading to up-regulation of the …
Kelch-like ECH-associated protein 1 (Keap1) cysteines, leading to up-regulation of the …
Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms: a randomized controlled trial
SE Geller, LP Shulman, RB Van Breemen… - Menopause, 2009 - journals.lww.com
Objective: The aim of this study was to evaluate the safety and efficacy of black cohosh and
red clover compared with placebo for the relief of menopausal vasomotor symptoms. Methods…
red clover compared with placebo for the relief of menopausal vasomotor symptoms. Methods…
Xanthohumol Isolated from Humulus lupulus Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase
…, AD Mesecar, RB van Breemen… - Chemical research in …, 2005 - ACS Publications
The female parts of hops (Humulus lupulus L.) show estrogenic effects as well as cancer
chemopreventive potential. We analyzed the chemopreventive mechanism of hops by studying …
chemopreventive potential. We analyzed the chemopreventive mechanism of hops by studying …