The superfamily of G-protein-coupled receptors (GPCRs) is very diverse in structure and
function and its members are among the most pursued targets for drug development. We …

Following the identification of the CC chemokines RANTES, MIP-1α and MIP-1β as major
human immunodeficiency virus (HIV)-suppressive factors produced by CD8 + T cells 1 , …

The superfamily of G-protein–coupled receptors (GPCRs) is one of the largest and most
studied families of proteins. We created Hidden Markov Models derived from sorted groups of …

Background Membrane proteins form key nodes in mediating the cell's interaction with the
surroundings, which is one of the main reasons why the majority of drug targets are …

Understanding differences in the repertoire of orthologous gene pairs is vital for interpretation
of pharmacological and physiological experiments if conclusions are conveyed between …

Gene variants of the FTO (fatso) gene have recently been strongly associated with body
mass index and obesity. The FTO gene is well conserved and found in a single copy in …

The super-family of G-protein coupled receptors (GPCRs) is one of the largest groups of
proteins in vertebrate species. The receptors are very diverse in structure and function but they …

The Adhesion family forms a large branch of the pharmacologically important superfamily of
G protein–coupled receptors (GPCRs). As Adhesion GPCRs increasingly receive attention …

We report seven new members of the superfamily of human G protein‐coupled receptors (GPCRs)
found by searches in the human genome databases, termed GPR100, GPR119, …

Dominant white, Dun, and Smoky are alleles at the Dominant white locus, which is one of the
major loci affecting plumage color in the domestic chicken. Both Dominant white and Dun …