User profiles for Ryo Kubota
 | Ryo KubotaKubota Vision Inc., Kubota Pharmaceutical Holdings Verified email at kubotavision.com Cited by 3124 |
Fuzzy programming for multiobjective job shop scheduling with fuzzy processing time and fuzzy duedate through genetic algorithms
M Sakawa, R Kubota - European Journal of operational research, 2000 - Elsevier
In this paper, by considering the imprecise or fuzzy nature of the data in real-world problems,
job shop scheduling with fuzzy processing time and fuzzy duedate is introduced. On the …
job shop scheduling with fuzzy processing time and fuzzy duedate is introduced. On the …
A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: molecular cloning, tissue expression, and chromosomal mapping
R Kubota, S Noda, Y Wang, S Minoshima, S Asakawa… - Genomics, 1997 - Elsevier
We have isolated a human cDNA clone encoding a novel acidic protein of MW 55,000 that we
designated “myocilin” since it has homology to myosin and is localized preferentially in the …
designated “myocilin” since it has homology to myosin and is localized preferentially in the …
Human BAC library: construction and rapid screening
S Asakawa, I Abe, Y Kudoh, N Kishi, Y Wang, R Kubota… - Gene, 1997 - Elsevier
We have constructed a human genomic bacterial artificial chromosome (BAC) library using
high molecular weight DNA from a pre-pro-B cell line, FLEB14-14, with a normal male diploid …
high molecular weight DNA from a pre-pro-B cell line, FLEB14-14, with a normal male diploid …
[HTML][HTML] Emixustat hydrochloride for geographic atrophy secondary to age-related macular degeneration: a randomized clinical trial
…, KG Csaky, JM Koester, JK Gregory, R Kubota - Ophthalmology, 2018 - Elsevier
Purpose To determine whether emixustat hydrochloride (emixustat) reduces the rate of
enlargement of geographic atrophy (GA) compared with placebo in subjects with age-related …
enlargement of geographic atrophy (GA) compared with placebo in subjects with age-related …
Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator
R Kubota, NL Boman, R David, S Mallikaarjun, S Patil… - Retina, 2012 - journals.lww.com
… Kubota, Ryo MD, PhD * ; Boman, Nancy L MD, PhD * ; David, Robert MD * ; Mallikaarjun,
Suresh PhD, FCP ‡ ; Patil, Shiva PhD ‡ ; Birch, David PhD † … Reprint requests: Ryo …
Suresh PhD, FCP ‡ ; Patil, Shiva PhD ‡ ; Birch, David PhD † … Reprint requests: Ryo …
[HTML][HTML] A rapid field detection system for citrus huanglongbing associated 'Candidatus Liberibacter asiaticus' from the psyllid vector, Diaphorina citri Kuwayama and …
ML Keremane, C Ramadugu, E Rodriguez, R Kubota… - Crop Protection, 2015 - Elsevier
‘Candidatus Liberibacter asiaticus’ (Las), associated with citrus huanglongbing (HLB or citrus
greening) is spread by Diaphorina citri Kuwayama, the Asian citrus psyllid. Psyllids can be …
greening) is spread by Diaphorina citri Kuwayama, the Asian citrus psyllid. Psyllids can be …
[HTML][HTML] Visual cycle modulation as an approach toward preservation of retinal integrity
…, V Kuksa, M Orme, I Scott, A Fawzi, R Kubota - PLoS …, 2015 - journals.plos.org
Increased exposure to blue or visible light, fluctuations in oxygen tension, and the excessive
accumulation of toxic retinoid byproducts places a tremendous amount of stress on the …
accumulation of toxic retinoid byproducts places a tremendous amount of stress on the …
[HTML][HTML] Real-time duplex applications of loop-mediated AMPlification (LAMP) by assimilating probes
R Kubota, DM Jenkins - International Journal of Molecular Sciences, 2015 - mdpi.com
Isothermal nucleic-acid amplification methods such as Loop-Mediated isothermal AMPlification
(LAMP) are increasingly appealing alternatives to PCR for use in portable diagnostic …
(LAMP) are increasingly appealing alternatives to PCR for use in portable diagnostic …
Phase 1, dose-ranging study of emixustat hydrochloride (ACU-4429), a novel visual cycle modulator, in healthy volunteers
Background: Emixustat hydrochloride (formerly ACU-4429) is a nonretinoid compound with
a unique mode of action in the retinal pigment epithelium, where it modulates the …
a unique mode of action in the retinal pigment epithelium, where it modulates the …
Phase ii, randomized, placebo-controlled, 90-day study of emixustat hydrochloride in geographic atrophy associated with dry age-related macular degeneration
Purpose: This study assessed the safety, tolerability, and pharmacodynamics of emixustat
hydrochloride (ACU-4429), a novel visual cycle modulator, in subjects with geographic …
hydrochloride (ACU-4429), a novel visual cycle modulator, in subjects with geographic …