Drug-induced block of cardiac hERG K + channels causes acquired long QT syndrome.
Here, we characterized the molecular mechanism of hERG block by two low-potency drugs (…

Background— Recent clinical electrophysiology studies and successful results of radiofrequency
catheter ablation therapy suggest that high-frequency focal activity in the pulmonary …

Block of cardiac hERG K + channels by the antihistamine terfenadine and the prokinetic agent
cisapride is associated with prolonged ventricular repolarization and an increased risk of …

Objective: In the heart, there are multiple supraventricular pacemakers involved in normal
pacemaking as well as arrhythmias and the objective was to determine the distribution of …

Carvedilol ((±)-1-(carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol), a β-adrenoceptor-blocking
agent with vasodilator properties, has been reported to produce dose-…

Objective: To study the morphology of small extracellular potentials localized to the sinoatrial
(SA) node and to elucidate its potential usefulness in evaluating SA node dysfunction. …

Effects of brief postganglionic vagal nerve stimulation on the activation sequence of the rabbit
sinoatrial (SA) node were investigated. Activation sequences in a small area (7 mm × 7 mm…

Purpose Pre-surgical diagnosis of skull base chondrosarcoma (SBC) is often challenging due
to the resemblance to chordoma. The goal of this study was to develop an optimal method …

Background Tractography is one way to predict the distribution of cortical functional domains
preoperatively. Diffusion tensor tractography (DTT) is commonly used in clinical practice, …

Background: Low-invasive stereotactic body radiation therapy is a novel anti-arrhythmic
strategy. The mechanisms underlying its effects against ventricular tachycardia/fibrillation (VT/VF…