Macrophage-microbe interaction: lessons learned from the pathogen Mycobacterium tuberculosis
S BoseDasgupta, J Pieters - Seminars in immunopathology, 2018 - Springer
… One microbe that is particularly successful at surviving within macrophages is the pathogen
Mycobacterium tuberculosis, which can efficiently manipulate the macrophage at several …
Mycobacterium tuberculosis, which can efficiently manipulate the macrophage at several …
Activated group 3 innate lymphoid cells promote T-cell–mediated immune responses
…, E Horvath, S Bose Dasgupta… - Proceedings of the …, 2014 - National Acad Sciences
… In the present study, we show that in mice where MHC class II is specifically deleted in ILC3s,
Ag-specific T-cell and T-dependent (TD) B-cell responses are impaired, demonstrating that …
Ag-specific T-cell and T-dependent (TD) B-cell responses are impaired, demonstrating that …
Mitochondria-dependent reactive oxygen species-mediated programmed cell death induced by 3, 3′-diindolylmethane through inhibition of F0F1-ATP synthase in …
… Mitochondrial F0F1-ATPase/ATP synthase is a ubiquitous enzyme that is responsible for
synthesis of ATP; therefore, it is critical for cell growth and survival. Resveratrol and isoflavones (…
synthesis of ATP; therefore, it is critical for cell growth and survival. Resveratrol and isoflavones (…
[HTML][HTML] Inflammatory stimuli reprogram macrophage phagocytosis to macropinocytosis for the rapid elimination of pathogens
S BoseDasgupta, J Pieters - PLoS pathogens, 2014 - journals.plos.org
… such as interferon-γ and tumor necrosis factor-α that is released from other immune cells.
Such macrophage activation is important to achieve a rapid and efficient clearance of microbial …
Such macrophage activation is important to achieve a rapid and efficient clearance of microbial …
[HTML][HTML] Coronin 1 regulates cognition and behavior through modulation of cAMP/protein kinase A signaling
R Jayachandran, X Liu, S BoseDasgupta, P Müller… - PLoS …, 2014 - journals.plos.org
… is the cyclic AMP/Protein kinase A pathway. We here show an essential role for coronin 1,
which is … We found that coronin 1 is specifically expressed in excitatory but not inhibitory …
which is … We found that coronin 1 is specifically expressed in excitatory but not inhibitory …
[HTML][HTML] The caspase-independent algorithm of programmed cell death in Leishmania induced by baicalein: the role of LdEndoG, LdFEN-1 and LdTatD as a DNA ' …
S BoseDasgupta, BB Das, S Sengupta… - Cell Death & …, 2008 - nature.com
In the post-genomic perspective, the quest of programmed cell death (PCD) mechanisms in
kinetoplastid parasites lies in the identification and characterization of cell death executer …
kinetoplastid parasites lies in the identification and characterization of cell death executer …
[HTML][HTML] ESX secretion system: The gatekeepers of mycobacterial survivability and pathogenesis
…, D Ghatak, P Das, S BoseDasgupta - European Journal of …, 2020 - akjournals.com
… membrane rupture, whereas ESX-2 is responsible for survivability, and ESX-3 is involved
in iron and zinc uptake and hindering of phagosome maturation. Additionally, ESX-4 …
in iron and zinc uptake and hindering of phagosome maturation. Additionally, ESX-4 …
[HTML][HTML] Striking the right balance determines TB or not TB
S BoseDasgupta, J Pieters - Frontiers in immunology, 2014 - frontiersin.org
… One of these is the protein coronin 1 (also known as P57 or TACO, for tryptophan aspartate
containing coat protein) that is present at the cell cortex of macrophages, and is actively …
containing coat protein) that is present at the cell cortex of macrophages, and is actively …
[HTML][HTML] The ultimate fate determinants of drug induced cell-death mechanisms in Trypanosomatids
P Das, S Saha, S BoseDasgupta - International Journal for Parasitology …, 2021 - Elsevier
Chemotherapy constitutes a major part of modern-day therapy for infectious and chronic
diseases. A drug is said to be effective if it can inhibit its target, induce stress, and thereby …
diseases. A drug is said to be effective if it can inhibit its target, induce stress, and thereby …
A novel ATP-binding cassette transporter, ABCG6 is involved in chemoresistance of Leishmania
S BoseDasgupta, A Ganguly, A Roy… - Molecular and …, 2008 - Elsevier
ATP-binding cassette (ABC) transporters constitute the biggest family of membrane proteins
involved in drug resistance and other biological activities. Resistance of leishmanial …
involved in drug resistance and other biological activities. Resistance of leishmanial …