User profiles for S. Dugar

Siddharth Dugar MD FCCP FCCM FASE

- Verified email at ccf.org - Cited by 950

Subhasish Dugar

- Verified email at economics.utah.edu - Cited by 749

Sumit Dugar

- Verified email at practicalaction.org.np - Cited by 552

[PDF][PDF] Sepsis and septic shock: Guideline-based management

S Dugar, C Choudhary, A Duggal - Cleve Clin J Med, 2020 - academia.edu
Sepsis is a life-threatening organ dysfunction that results from the body’s response to infection.
It requires prompt recognition, appropriate antibiotics, careful hemodynamic support, and …

Citizen science for hydrological risk reduction and resilience building

…, J Bhusal, K Cieslik, J Clark, S Dugar… - Wiley …, 2018 - Wiley Online Library
… Such projects work best when there is community buy‐in, when their purpose(s) are
clearly defined at the outset, and when the motivations and skillsets of all participants and …

[HTML][HTML] The impact of right ventricular injury on the mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis

R Sato, S Dugar, W Cheungpasitporn, M Schleicher… - Critical Care, 2021 - Springer
… We also statistically assessed publication bias using Egger’s regression test and found no
… as you give appropriate credit to the original author(s) and the source, provide a link to the …

Progressive transforming growth factor β1–induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor

…, A Murphy, S Chakravarty, S Dugar… - American journal of …, 2005 - atsjournals.org
Pulmonary fibrosis is characterized by chronic scar formation and deposition of extracellular
matrix, resulting in impaired lung function and respiratory failure. Idiopathic pulmonary …

Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies

…, B Shabane, K Erion, R Masand, S Dugar… - The EMBO …, 2023 - embopress.org
The maintenance of cellular function relies on the close regulation of adenosine triphosphate
(ATP) synthesis and hydrolysis. ATP hydrolysis by mitochondrial ATP Synthase (CV) is …

Targeting endogenous transforming growth factor β receptor signaling in Smad4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype

…, L Higgins, G McEnroe, S Chakravarty, S Dugar… - Cancer research, 2004 - AACR
… Our study demonstrates that, in PC cell lines that have escaped from TGFβ’s tumor suppressive
function because of Smad4 deletion, the steady state levels of phosphorylated R-Smads, …

Choice of routes in congested traffic networks: Experimental tests of the Braess Paradox

A Rapoport, T Kugler, S Dugar, EJ Gisches - Games and Economic …, 2009 - Elsevier
… Clicking with the mouse on a link changed the link’s color on the screen to indicate the
player’s choice. The player was then asked to verify her choice of route by clicking on a “Yes” …

Inhibition of Growth and Metastasis of Mouse Mammary Carcinoma by Selective Inhibitor of Transforming Growth Factor-β Type I Receptor Kinase In vivo

…, A Protter, A Murphy, J Chakravarty, S Dugar… - Clinical cancer …, 2006 - AACR
Purpose: Transforming growth factor-β (TGF-β) suppresses tumor development by inhibiting
cellular proliferation, inducing differentiation and apoptosis, and maintaining genomic …

Mavrilimumab in patients with severe COVID-19 pneumonia and systemic hyperinflammation (MASH-COVID): an investigator initiated, multicentre, double-blind …

…, S Spencer, A Goyanes, D Sahoo, S Dugar… - The Lancet …, 2021 - thelancet.com
Background In patients with COVID-19, granulocyte-macrophage colony stimulating factor (GM-CSF)
might be a mediator of the hyperactive inflammatory response associated with …

2-Azetidinone cholesterol absorption inhibitors: structure− activity relationships on the heterocyclic nucleus

…, MA Caplen, MS Domalski, S Dugar… - Journal of medicinal …, 1996 - ACS Publications
A series of azetidinone cholesterol absorption inhibitors related to SCH 48461 ((−)-6) has
been prepared, and compounds were evaluated for their ability to inhibit hepatic cholesteryl …