Cloned glutamate receptors

M Hollmann, S Heinemann - Annual review of neuroscience, 1994 - annualreviews.org
The application of molecular cloning technology to the study of the glutamate receptor system
has led to an explosion of knowledge about the structure, expression, and function of this …

[PDF][PDF] Molecular and cellular aspects of nicotine abuse

JA Dani, S Heinemann - Neuron, 1996 - cell.com
… activation and inactivation is caused by a smoker’s level of nicotine (Clarke, 1991; Wonnacott,
… by the same reward pathways abstinence (such as overnight), a smoker’s nicotine lev- …

Regulation of cell function by methionine oxidation and reduction

T Hoshi, SH Heinemann - The Journal of physiology, 2001 - Wiley Online Library
Reactive oxygen species (ROS) are generated during normal cellular activity and may exist
in excess in some pathophysiological conditions, such as inflammation or reperfusion injury. …

Cloning by functional expression of a member of the glutamate receptor family

…, A O'Shea-Greenfield, SW Rogers, S Heinemann - Nature, 1989 - nature.com
We have isolated a complementary DNA clone by screening a rat brain cDNA library for
expression of kainate-gated ion channels in Xenopus oocytes. The cDNA encodes a single …

Ca2+ Permeability of KA-AMPA—Gated Glutamate Receptor Channels Depends on Subunit Composition

M Hollmann, M Hartley, S Heinemann - Science, 1991 - science.org
NMDA (N-methyl -D-aspartate) receptors and non-NMDA receptors represent the two major
classes of ion channel-linked glutamate receptors. Unlike the NMDA receptor channels, non-…

α9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells

…, DS Johnson, J Boulter, DE Vetter, S Heinemann - Cell, 1994 - cell.com
We report the isolation and functional characterization of a member of the nicotinic acetylcholine
receptor subunit gene family, cc9. Xenopus oocytes injected with a9 cRNA express a …

Calcium channel characteristics conferred on the sodium channel by single mutations

SH Heinemann, H Terlau, W Stühmer, K Imoto, S Numa - Nature, 1992 - nature.com
… М Y 731-743 | Skel eta о у ш т о в о м м S у мү 509-62) … S 1 703 - 1720 Skell eta 1 p IEIIIS ;
A: GWDGLLN i 524 - … Numa S. Harvey lect 83, 121-165 (1989), Terlau, H, et al FE8S lett. 293, …

Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels

…, MC Stensmyr, R Heller, SH Heinemann… - Nature, 2008 - nature.com
From worm to man, many odorant signals are perceived by the binding of volatile ligands to
odorant receptors 1 that belong to the G-protein-coupled receptor (GPCR) family 2 . They …

Inactivation properties of voltage-gated K+ channels altered by presence of β-subunit

J Rettig, SH Heinemann, F Wunder, C Lorra, DN Parcej… - Nature, 1994 - nature.com
… The remaining S ee slow Current decay is similar to that in a or c under oxidizing conditions
and is attributed to the so-called C-type inactivation involving the channel pore structure"". f. …

Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the …

…, JIM Boulter, E Deneris, S Heinemann… - Journal of …, 1989 - Wiley Online Library
… Nine different [ 35 S]‐complementary ribonucleic acid (cRNA) probes were used in the
present study to map the distribution of these nAChR subunit mRNAs throughout the central …