Nematode ligand-gated chloride channels: an appraisal of their involvement in macrocyclic lactone resistance and prospects for developing molecular markers
S McCavera, TK Walsh, AJ Wolstenholme - Parasitology, 2007 - cambridge.org
Ligand-gated chloride channels, including the glutamate-(GluCl) and GABA-gated channels,
are the targets of the macrocyclic lactone (ML) family of anthelmintics. Changes in the …
are the targets of the macrocyclic lactone (ML) family of anthelmintics. Changes in the …
An ivermectin-sensitive glutamate-gated chloride channel from the parasitic nematode Haemonchus contortus
S McCavera, AT Rogers, DM Yates, DJ Woods… - Molecular …, 2009 - ASPET
… before perfusion through the oocyte chamber for 5 to 10 s. A washing period of 5 min was
allowed … The cells were further disrupted by sonication in three 10-s bursts on medium power. …
allowed … The cells were further disrupted by sonication in three 10-s bursts on medium power. …
The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy
…, C Rada, E Bailey, S McCavera… - EMBO molecular …, 2014 - embopress.org
Abnormal uterine activity in pregnancy causes a range of important clinical disorders, including
preterm birth, dysfunctional labour and post‐partum haemorrhage. Uterine contractile …
preterm birth, dysfunctional labour and post‐partum haemorrhage. Uterine contractile …
Differential state-dependent modification of inactivation-deficient Nav1. 6 sodium channels by the pyrethroid insecticides S-bioallethrin, tefluthrin and deltamethrin
SJ McCavera, DM Soderlund - Neurotoxicology, 2012 - Elsevier
… repeated channel activation, and S-bioallethrin modification is … By contrast modification by
S-bioallethrin following short … of deltamethrin and tefluthrin (but not S-bioallethrin) to Na v 1.6…
S-bioallethrin following short … of deltamethrin and tefluthrin (but not S-bioallethrin) to Na v 1.6…
Music: Striking the right notes
S McCavera - British Journal of Special Education, 1991 - Wiley Online Library
… Again, the provision for music is resourced in a variety of ways, both from the school’s
own staff and from external groups. Music is seen as an essential ingredient in the school’s …
own staff and from external groups. Music is seen as an essential ingredient in the school’s …
A High-Throughput Electrophysiology Assay Identifies Inhibitors of the Inwardly Rectifying Potassium Channel Kir7.1
…, C McCloskey, S McCavera… - Journal of …, 2015 - journals.sagepub.com
… MRT00200769’s potential as a therapeutic is limited by its hERG activity, which we were
unable to reduce in our initial medicinal chemistry. Of uppermost importance, however, was the …
unable to reduce in our initial medicinal chemistry. Of uppermost importance, however, was the …
[PDF][PDF] An invermectin sensitive ion channel from haemonchus contortus
SJC McCavera - 2008 - core.ac.uk
… Finally I would like to thank my parents, Peter and Trish McCavera and my sister Fiona,
who, without a doubt, are my greatest source of strength and inspiration. It was their belief that I …
who, without a doubt, are my greatest source of strength and inspiration. It was their belief that I …
Assessing the validity and accuracy of online videos on vaccine health risks
M Murphy, FA Nanadiego, L McCavera… - Clinical …, 2020 - journals.sagepub.com
… Several factors that affect any particular patient’s response to immunization may include, but
… Therefore, videos that insinuated or insisted that an individual patient’s suffering strongly …
… Therefore, videos that insinuated or insisted that an individual patient’s suffering strongly …
A glycine residue essential for high ivermectin sensitivity in Cys-loop ion channel receptors
… In this experiment, we repeatedly applied ∼1 s applications of a constant EC 10 –EC 20
glycine concentration that alternated with 4 s applications of progressively increasing ivermectin …
glycine concentration that alternated with 4 s applications of progressively increasing ivermectin …
Altered avr-14B gene transcription patterns in ivermectin-resistant isolates of the cattle parasites, Cooperia oncophora and Ostertagia ostertagi
A El-Abdellati, J De Graef, A Van Zeveren… - International journal for …, 2011 - Elsevier
… Single-stranded template DNA was isolated using the designated Vacuum Prep Tool (Biotage)
according to the manufacturer’s instructions and added to 40 μl of sequencing primer (…
according to the manufacturer’s instructions and added to 40 μl of sequencing primer (…