Kainate receptors ( KAR s) consist of a family of ionotropic glutamate receptors composed of
the combinations of five subunits, GluK1–GluK5. Although KAR s display close structural …

INTRODUCTION The cerebral cortex is a cellularly heterogeneous structure whose neuronal
circuits underlie high-order cognitive and sensorimotor information processing. Neocortical …

During corticogenesis, ventricular zone progenitors sequentially generate distinct subtypes
of neurons, accounting for the diversity of neocortical cells and the circuits they form. While …

The diverse subtypes of excitatory neurons that populate the neocortex are born from apical
progenitors located in the ventricular zone. During corticogenesis, apical progenitors …

Interconnectivity between neocortical areas is critical for sensory integration and sensorimotor
transformations 1 , 2 , 3 , 4 , 5 – 6 . These functions are mediated by heterogeneous inter-…

Neurons of the neocortex are organized into six radial layers, which have appeared at different
times during evolution, with the superficial layers representing a more recent acquisition. …

The appropriate trafficking of glutamate receptors to synapses is crucial for basic synaptic
function and synaptic plasticity. It is now accepted that NMDA receptors (NMDARs) internalize …

Input from the sensory organs is required to pattern neurons into topographical maps during
development. Dendritic complexity critically determines this patterning process; yet, how …

Kainate receptors (KARs) consist of a class of ionotropic glutamate receptors, which exert
diverse pre- and postsynaptic functions through complex signaling regulating the activity of …

Distinct subtypes of ionotropic glutamate receptors can segregate to specific synaptic inputs
in a given neuron. Using functional mapping by focal glutamate uncaging in CA3 pyramidal …