User profiles for Sabrina Heng

Sabrina Heng

Centre for Nanoscale BioPhotonics, University of Adelaide
Verified email at adelaide.edu.au
Cited by 1066

Sensing with suspended-core optical fibers

…, EP Schartner, A François, S Heng… - Optical Fiber …, 2010 - Elsevier
The development of optical fibers with suspended cores has enabled the demonstration of a
range of powerful new techniques for chemical and biological sensing. Here the fabrication, …

Fluorescence-based aluminum ion sensing using a surface-functionalized microstructured optical fiber

SC Warren-Smith, S Heng, H Ebendorff-Heidepriem… - Langmuir, 2011 - ACS Publications
The first microstructured optical fiber-based sensor platform for aluminum ions using a
surface-attached derivative of lumogallion (3), a known fluorescence-based indicator, has been …

A library of novel allosteric inhibitors against fructose 1, 6-bisphosphatase

S Heng, KR Gryncel, ER Kantrowitz - Bioorganic & medicinal chemistry, 2009 - Elsevier
The identification of a proper lead compound for fructose 1,6-bisphosphatase (FBPase) is a
critical step in the process of developing novel therapeutics against type-2 diabetes. Herein, …

Nanoliter-scale, regenerable ion sensor: sensing with a surface functionalized microstructured optical fibre

S Heng, MC Nguyen, R Kostecki, TM Monro… - RSC advances, 2013 - pubs.rsc.org
The first nanoliter-scale regenerable ion sensor based on a microstructured optical fibre (MOF)
is reported. The air holes of the MOF are functionalized with a monoazacrown bearing …

Dual sensor for Cd (II) and Ca (II): selective nanoliter-scale sensing of metal ions

S Heng, AM Mak, DB Stubing, TM Monro… - Analytical …, 2014 - ACS Publications
The first selective, dual sensor for Ca 2+ and Cd 2+ capable of detection at 100 pM
concentrations was designed and synthesized. The experimental observations made for the MC-…

Designing inhibitors against fructose 1, 6-bisphosphatase: Exploring natural products for novel inhibitor scaffolds

S Heng, KM Harris, ER Kantrowitz - European journal of medicinal …, 2010 - Elsevier
Natural products often contain unusual scaffold structures that may be elaborated by
combinatorial methods to develop new drug-like molecules. Visual inspection of more than 128 …

Biological hydrogen peroxide detection with aryl boronate and benzil BODIPY-based fluorescent probes

…, DW Drumm, X Zhang, PK Capon, S Heng… - Sensors and Actuators B …, 2018 - Elsevier
The detection of hydrogen peroxide (H 2 O 2 ) using fluorescent probes is critical to the
study of oxidative stress in biological environments. Two important sensing architectures for …

Microstructured optical fiber-based biosensors: reversible and nanoliter-scale measurement of zinc ions

S Heng, CA McDevitt, R Kostecki… - … applied materials & …, 2016 - ACS Publications
Sensing platforms that allow rapid and efficient detection of metal ions would have applications
in disease diagnosis and study, as well as environmental sensing. Here, we report the …

New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds

S Heng, W Tieu, S Hautmann, K Kuan… - Bioorganic & medicinal …, 2011 - Elsevier
We present a new class of inhibitors of pancreatic cholesterol esterase (CEase) based on ‘priviledged’
5-benzylidenerhodanine and 5-benzylidene-2,4-thiazolidinedione structural …

Taming the light in microstructured optical fibers for sensing

…, SC Warren‐Smith, LV Nguyen, S Heng… - … Journal of Applied …, 2015 - Wiley Online Library
In this review, we examine recent developments in the field of chemical and biological sensing
utilizing suspended‐core, exposed‐core, and hollow‐core microstructured optical fibers. …