User profiles for Sabrina Heng
Sabrina HengCentre for Nanoscale BioPhotonics, University of Adelaide Verified email at adelaide.edu.au Cited by 1066 |
Sensing with suspended-core optical fibers
The development of optical fibers with suspended cores has enabled the demonstration of a
range of powerful new techniques for chemical and biological sensing. Here the fabrication, …
range of powerful new techniques for chemical and biological sensing. Here the fabrication, …
Fluorescence-based aluminum ion sensing using a surface-functionalized microstructured optical fiber
The first microstructured optical fiber-based sensor platform for aluminum ions using a
surface-attached derivative of lumogallion (3), a known fluorescence-based indicator, has been …
surface-attached derivative of lumogallion (3), a known fluorescence-based indicator, has been …
A library of novel allosteric inhibitors against fructose 1, 6-bisphosphatase
S Heng, KR Gryncel, ER Kantrowitz - Bioorganic & medicinal chemistry, 2009 - Elsevier
The identification of a proper lead compound for fructose 1,6-bisphosphatase (FBPase) is a
critical step in the process of developing novel therapeutics against type-2 diabetes. Herein, …
critical step in the process of developing novel therapeutics against type-2 diabetes. Herein, …
Nanoliter-scale, regenerable ion sensor: sensing with a surface functionalized microstructured optical fibre
The first nanoliter-scale regenerable ion sensor based on a microstructured optical fibre (MOF)
is reported. The air holes of the MOF are functionalized with a monoazacrown bearing …
is reported. The air holes of the MOF are functionalized with a monoazacrown bearing …
Dual sensor for Cd (II) and Ca (II): selective nanoliter-scale sensing of metal ions
The first selective, dual sensor for Ca 2+ and Cd 2+ capable of detection at 100 pM
concentrations was designed and synthesized. The experimental observations made for the MC-…
concentrations was designed and synthesized. The experimental observations made for the MC-…
Designing inhibitors against fructose 1, 6-bisphosphatase: Exploring natural products for novel inhibitor scaffolds
S Heng, KM Harris, ER Kantrowitz - European journal of medicinal …, 2010 - Elsevier
Natural products often contain unusual scaffold structures that may be elaborated by
combinatorial methods to develop new drug-like molecules. Visual inspection of more than 128 …
combinatorial methods to develop new drug-like molecules. Visual inspection of more than 128 …
Biological hydrogen peroxide detection with aryl boronate and benzil BODIPY-based fluorescent probes
The detection of hydrogen peroxide (H 2 O 2 ) using fluorescent probes is critical to the
study of oxidative stress in biological environments. Two important sensing architectures for …
study of oxidative stress in biological environments. Two important sensing architectures for …
Microstructured optical fiber-based biosensors: reversible and nanoliter-scale measurement of zinc ions
Sensing platforms that allow rapid and efficient detection of metal ions would have applications
in disease diagnosis and study, as well as environmental sensing. Here, we report the …
in disease diagnosis and study, as well as environmental sensing. Here, we report the …
New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds
We present a new class of inhibitors of pancreatic cholesterol esterase (CEase) based on ‘priviledged’
5-benzylidenerhodanine and 5-benzylidene-2,4-thiazolidinedione structural …
5-benzylidenerhodanine and 5-benzylidene-2,4-thiazolidinedione structural …
Taming the light in microstructured optical fibers for sensing
In this review, we examine recent developments in the field of chemical and biological sensing
utilizing suspended‐core, exposed‐core, and hollow‐core microstructured optical fibers. …
utilizing suspended‐core, exposed‐core, and hollow‐core microstructured optical fibers. …