Aging-related salivary dysfunction commonly induces the poor oral health, including decreased
saliva flow and dental caries. Although the clinical significance of the salivary glands is …

The activation of eukaryotic heat shock protein (Hsp) gene expression occurs in response to
a wide variety of cellular stresses including heat shock, hydrogen peroxide, uncoupled …

In the present study we developed doxorubicin-loaded solid lipid nanoparticles (SLN-Dox)
using biocompatible compounds, assessed the in vitro hemolytic effect, and examined their in …

The feasibility of identifying cancer cells by measuring the refractive index (RI) distribution
across a single live cell with ultrahigh resolution full-field optical coherence microscopy (FF-…

Background Epigallocatechin-3-gallate (EGCG), one of the major catechins in green tea, is
a potential chemopreventive agent for various cancers. The aim of this study was to examine …

… Authors: Se-Ra Park, Dong-Jae Kim, Seung-Hyun Han, Min-Jung Kang, Jun-Young Lee,
Yu-Jin Jeong, Sang-Jin Lee, Tae-Hyoun Kim, Sang-Gun Ahn, Jung-Hoon Yoon, … Sang-Gun Ahn …

Heat shock transcription factor 1 (HSF1) is activated by pathophysiologic stresses and
activation leads to an increased cellular level of heat shock proteins (Hsp(s)). Although the …

Dynamic membrane remodeling during intracellular trafficking is controlled by the intricate
interplay between lipids and proteins. BAR domains are modules that participate in endocytic …

Phenolic constituents of virgin olive oil are reported to have antitumor activity. However, the
underlying molecular mechanisms and specific target proteins of virgin olive oil remain to be …

To enhance the ability of indirubin derivatives to inhibit CDK2/cyclin E, a target of anticancer
agents, we designed and synthesized a new series of indirubin-3′-oxime derivatives with …