User profiles for Sean G. Forrester

Sean Forrester

Ontario Tech University
Verified email at ontariotechu.ca
Cited by 826

Extracting protostrongylid nematode larvae from ungulate feces

SG Forrester, MW Lankester - Journal of Wildlife Diseases, 1997 - meridian.allenpress.com
A major weakness of the Baermann funnel technique for extracting nematode larvae from
feces is the funnel. As many as 67% of Parelaphostrongylus tenuis first-stage larvae lodged on …

A glutamate-gated chloride channel subunit from Haemonchus contortus:: Expression in a mammalian cell line, ligand binding, and modulation of anthelmintic binding …

SG Forrester, RK Prichard, RN Beech - Biochemical pharmacology, 2002 - Elsevier
Glutamate-gated chloride channels (GluCls) are inhibitory ion channels that are sensitive to
the antiparasitic drugs ivermectin (IVM) and moxidectin (MOX). We have transiently …

A dopamine-gated ion channel (HcGGR3*) from Haemonchus contortus is expressed in the cervical papillae and is associated with macrocyclic lactone resistance

…, SZ Siddiqui, RK Prichard, SG Forrester - Molecular and …, 2009 - Elsevier
Haemonchus contortus, a parasitic nematode of great economic importance, is a major
challenge for the livestock industries. The parasite is controlled by nematocidal drugs, several of …

Haemonchus contortus: HcGluCla expressed in Xenopus oocytes forms a glutamate-gated ion channel that is activated by ibotenate and the antiparasitic drug …

SG Forrester, RK Prichard, JA Dent… - Molecular and biochemical …, 2003 - Elsevier
Ion channels are targets for many drugs including insecticides and anthelminthic agents
such as ivermectin (IVM) and moxidectin (MOX). IVM has been shown to activate glutamate-…

Tegumental expression of a novel type II receptor serine/threonine kinase (SmRK2) in Schistosoma mansoni

SG Forrester, PW Warfel, EJ Pearce - Molecular and Biochemical …, 2004 - Elsevier
The TGF-β family of receptor serine/threonine kinases (RSTKs) is responsible for a diverse
array of functions in metazoans. Here, we describe the isolation of SmRK2, a type II RSTK …

[HTML][HTML] Recent duplication and functional divergence in parasitic nematode levamisole-sensitive acetylcholine receptors

TB Duguet, CL Charvet, SG Forrester… - PLoS Neglected …, 2016 - journals.plos.org
Helminth parasites rely on fast-synaptic transmission in their neuromusculature to experience
the outside world and respond to it. Acetylcholine plays a pivotal role in this and its …

Cloning, sequencing, and developmental expression levels of a novel glutamate-gated chloride channel homologue in the parasitic NematodeHaemonchus contortus

SG Forrester, FF Hamdan, RK Prichard… - … and biophysical research …, 1999 - Elsevier
Glutamate-gated chloride channels (GluCls) are the proposed site of action for macrocyclic
lactone anthelminthics such as ivermectin (IVM) and the milbemycins such as moxidectin (…

An UNC‐49 GABA receptor subunit from the parasitic nematode Haemonchus contortus is associated with enhanced GABA sensitivity in nematode heteromeric …

…, DDR Brown, VTS Rao, SG Forrester - Journal of …, 2010 - Wiley Online Library
… Address correspondence and reprint requests to Sean G. Forrester, Faculty of Science,
University of Ontario Institute of Technology, 2000 Simcoe Street North, Oshawa ON L1H 7K4 …

Pharmacological characterization of the Haemonchus contortus GABA-gated chloride channel, Hco-UNC-49: modulation by macrocyclic lactone anthelmintics and a …

DDR Brown, SZ Siddiqui, MD Kaji, SG Forrester - Veterinary parasitology, 2012 - Elsevier
Invertebrate ligand-gated chloride channels are well recognized as important targets for several
insecticides and anthlemintics. Hco-UNC-49 is a GABA-gated chloride channel from the …

Association of ion-channel genotype and macrocyclic lactone sensitivity traits in Haemonchus contortus

…, N Levitt, M Cambos, S Zhou, SG Forrester - Molecular and …, 2010 - Elsevier
Resistance to macrocyclic lactones in the strongylid parasite of sheep, Haemonchus
contortus, is associated with specific alleles of several genes, including those encoding ligand-…