Ion channels activated by mechanical inputs are important force sensing molecules in a wide
array of mammalian cells and tissues. The transient receptor potential channel, TRPV4, is …

An Australian estuarine isolate of Penicillium sp. MST-MF667 yielded 3 tetrapeptides named
the bilaids with an unusual alternating LDLD chirality. Given their resemblance to known …

Cytotoxic T lymphocytes (CTLs) lyse target cells by delivering lytic granules that contain the
pore former perforin to the cytotoxic immunological synapse. Here, we establish that …

Phosphorylation of residues in the C-terminal tail of the µ-opioid receptor (MOPr) is thought
to be a key step in desensitization and internalization. Phosphorylation of C-terminal S/T …

Ionic currents can be evoked by mechanical inputs applied directly at the cell-substrate
interface. These ionic currents are mediated by mechanically activated ion channels, where the …

Cannabinoids are psychoactive compounds with many pharmacological properties such as
analgesia, sedation and catalepsy most of which are mediated by cannabinoid CB 1 …

In this study we evaluated the effects of sex difference and also sex hormones on the
naloxone-precipitated morphine withdrawal in both orchidectomized (ORC) male and …

One-third of lithium-treated men complain from sexual dysfunction, although the exact
mechanisms of which are not yet known. In this study we investigated the effect of chronic lithium (…

BACKGROUND: Despite its apparent anti-apoptotic effect, lithium impairs endothelium-dependent
vasorelaxation in various tissues. In this study, we assessed the effect of lithium …

We have previously shown that FK-506 (tacrolimus) improves random-pattern skin flap survival
in normal animals. 1 Skin flap survival is decreased in cigarette smokers, presumably by …