[HTML][HTML] Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes

…, N Morikawa, Y Saito, Y Masuho, S Matsumoto - Journal of Biological …, 2000 - ASBMB
Recently cDNA encoding the histamine H3 receptor was isolated after 15 years of considerable
research. However, several studies have proposed heterogeneity of the H3 receptor. We …

Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor

…, T Saito, M Matsumoto, J Takasaki, S Matsumoto… - Biochemical and …, 2005 - Elsevier
A lysophospholipid series, such as lysophosphatidic acid, lysophosphatidylserine, and
lysophosphatidylcholine (LPC), is a bioactive lipid mediator with diverse physiological and …

Molecular identification of nicotinic acid receptor

T Soga, M Kamohara, J Takasaki, S Matsumoto… - Biochemical and …, 2003 - Elsevier
Nicotinic acid and its derivative, Acipimox, have been widely used in the treatment of
hyperlipidemia. Pharmacological studies have demonstrated that they exert the beneficial effect …

Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2

S Matsumoto, C Yamazaki… - Proceedings of the …, 2006 - National Acad Sciences
Prokineticins, multifunctional secreted proteins, activate two endogenous G protein-coupled
receptors PKR1 and PKR2. From in situ analysis of the mouse brain, we discovered that …

The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis

…, A Suwa, M Asaumi, S Matsumoto… - Proceedings of the …, 2006 - National Acad Sciences
Fatty acid synthesis in the central nervous system is implicated in the control of food intake
and energy expenditure. An intermediate in this pathway, malonyl-CoA, mediates these effects…

Angiopoietin-related growth factor antagonizes obesity and insulin resistance

…, H Maekawa, T Miyamoto, K Miyata, S Matsumoto… - Nature medicine, 2005 - nature.com
Angiopoietin-related growth factor (AGF), a member of the angiopoietin-like protein (Angptl)
family, is secreted predominantly from the liver into the systemic circulation. Here, we show …

Inhibition of angiogenesis and vascular leakiness by angiopoietin-related protein 4

…, K Yasunaga, K Hamada, K Miyata, S Matsumoto… - Cancer research, 2003 - AACR
Angiopoietins and angiopoietin-related proteins (ARPs) have been shown to regulate
angiogenesis, a process essential for various neovascular diseases including tumors. Here, we …

Molecular cloning and characterization of prokineticin receptors

T Soga, S Matsumoto, T Oda, T Saito, H Hiyama… - … et Biophysica Acta (BBA …, 2002 - Elsevier
Recent studies have identified two novel biofunctional proteins, termed prokineticin 1/EG-VEGF
and prokineticin 2, which were mammalian homologues of mamba MIT1 and frog Bv8. …

Expression and localization of matrix metalloproteinase-12 in the aorta of cholesterol-fed rabbits: relationship to lesion development

S Matsumoto, T Kobayashi, M Katoh, S Saito… - The American journal of …, 1998 - Elsevier
Degradation of extracellular matrix (ECM) proteins in the aorta is a critical step for the
development of atherosclerosis. Expression of matrix metalloproteinase (MMP)-12 (macrophage …

Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration

…, K Yasunaga, Y Ito, S Matsumoto… - Proceedings of the …, 2003 - National Acad Sciences
We report here the identification of an angiopoietin-related growth factor (AGF). To examine
the biological function of AGF in vivo, we created transgenic mice expressing AGF in …