[PDF][PDF] Human brown adipocyte thermogenesis is driven by β2-AR stimulation
…, EN Kuipers, MC Severinsen, VH Jensen, S Miard… - Cell metabolism, 2020 - cell.com
Stimulation of brown adipose tissue (BAT) thermogenesis in humans has emerged as an
attractive target to improve metabolic health. Pharmacological stimulations targeting the β 3 -…
attractive target to improve metabolic health. Pharmacological stimulations targeting the β 3 -…
Cyclin D3 promotes adipogenesis through activation of peroxisome proliferator-activated receptor γ
…, I Iankova, A Abella, S Assou, S Miard… - … and Cellular Biology, 2005 - Taylor & Francis
In addition to their role in cell cycle progression, new data reveal an emerging role of D-type
cyclins in transcriptional regulation and cellular differentiation processes. Using 3T3-L1 cell …
cyclins in transcriptional regulation and cellular differentiation processes. Using 3T3-L1 cell …
[HTML][HTML] Impaired pancreatic growth, β cell mass, and β cell function in E2F1 –/– mice
L Fajas, JS Annicotte, S Miard, D Sarruf… - The Journal of …, 2004 - Am Soc Clin Investig
We evaluated the effects of E2F1 on glucose homeostasis using E2F1 –/– mice. E2F1 –/–
mice show an overall reduction in pancreatic size as the result of impaired postnatal …
mice show an overall reduction in pancreatic size as the result of impaired postnatal …
[HTML][HTML] Hypoxia upregulates Malat1 expression through a CaMKK/AMPK/HIF-1α axis
S Sallé-Lefort, S Miard, MA Nolin… - International …, 2016 - spandidos-publications.com
Increased expression levels of the long non-coding RNA metastasis-associated lung
adenocarcinoma transcript 1 (Malat1) have been associated with enhanced proliferation and …
adenocarcinoma transcript 1 (Malat1) have been associated with enhanced proliferation and …
Peroxisome proliferator-activated receptor γ regulates E-cadherin expression and inhibits growth and invasion of prostate cancer
JS Annicotte, I Iankova, S Miard, V Fritz… - … and Cellular Biology, 2006 - Taylor & Francis
Peroxisome proliferator-activated receptor γ (PPARγ) might not be permissive to ligand
activation in prostate cancer cells. Association of PPARγ with repressing factors or …
activation in prostate cancer cells. Association of PPARγ with repressing factors or …
[PDF][PDF] The retinoblastoma-histone deacetylase 3 complex inhibits PPARγ and adipocyte differentiation
…, J Hansen, K Kristiansen, MB Debril, S Miard… - Developmental cell, 2002 - cell.com
The retinoblastoma protein (RB) has previously been shown to facilitate adipocyte
differentiation by inducing cell cycle arrest and enhancing the transactivation by the adipogenic …
differentiation by inducing cell cycle arrest and enhancing the transactivation by the adipogenic …
[HTML][HTML] Selective cyclo-oxygenase-2 inhibitors impair adipocyte differentiation through inhibition of the clonal expansion phase
Selective cyclo-oxygenase-2 (COX-2) inhibitors are nonsteroidal antiinflammatory drugs
used in the management of inflammatory diseases. We demonstrate here that inhibition of the …
used in the management of inflammatory diseases. We demonstrate here that inhibition of the …
[PDF][PDF] IGFBP-2 partly mediates the early metabolic improvements caused by bariatric surgery
…, Z Hao, MB Mumphrey, RL Townsend, S Miard… - Cell Reports …, 2021 - cell.com
Insulin-like growth factor-binding protein (IGFBP)-2 is a circulating biomarker of cardiometabolic
health. Here, we report that circulating IGFBP-2 concentrations robustly increase after …
health. Here, we report that circulating IGFBP-2 concentrations robustly increase after …
PPARγ controls cell proliferation and apoptosis in an RB-dependent manner
L Fajas, V Egler, R Reiter, S Miard, AM Lefebvre… - Oncogene, 2003 - nature.com
The nuclear receptor PPARγ is implicated in the control of cell proliferation and apoptosis.
However, the molecular mechanisms by which it controls these processes remain largely …
However, the molecular mechanisms by which it controls these processes remain largely …
Loss of OcaB prevents age-induced fat accretion and insulin resistance by altering B-lymphocyte transition and promoting energy expenditure
S Carter, S Miard, A Caron, S Sallé-Lefort… - Diabetes, 2018 - Am Diabetes Assoc
The current demographic shift toward an aging population has led to a robust increase in the
prevalence of age-associated metabolic disorders. Recent studies have demonstrated that …
prevalence of age-associated metabolic disorders. Recent studies have demonstrated that …