User profiles for Stefania Mariggiò

Stefania Mariggio

Institute of Protein Biochemistry
Verified email at ibp.cnr.it
Cited by 1750

Selective regulation of Gq signaling by G protein-coupled receptor kinase 2: direct interaction of kinase N terminus with activated Gαq

M Sallese, S Mariggiò, E D'Urbano, L Iacovelli… - Molecular …, 2000 - ASPET
In this study, we investigated the regulation of different G protein-coupled receptor (GPCR)-stimulated
signaling pathways by GPCR kinase 2 (GRK2). We used thyrotropin receptor, …

The emerging physiological roles of the glycerophosphodiesterase family

…, N Ohshima, L Grauso, N Yanaka, S Mariggiò - The FEBS …, 2014 - Wiley Online Library
The glycerophosphodiester phosphodiesterases are evolutionarily conserved proteins that
have been linked to several patho/physiological functions, comprising bacterial pathogenicity …

A 14-3-3γ dimer-based scaffold bridges CtBP1-S/BARS to PI (4) KIIIβ to regulate post-Golgi carrier formation

C Valente, G Turacchio, S Mariggiò, A Pagliuso… - Nature cell …, 2012 - nature.com
Large pleiomorphic carriers leave the Golgi complex for the plasma membrane by en bloc
extrusion of specialized tubular domains, which then undergo fission. Several components of …

[HTML][HTML] G protein-coupled receptor kinase GRK4: molecular analysis of the four isoforms and ultrastructural localization in spermatozoa and germinal cells

M Sallese, S Mariggio, G Collodel, E Moretti… - Journal of Biological …, 1997 - ASBMB
G protein-coupled receptor kinase 4 (GRK4) presents some peculiar characteristics that make
it a unique member within the GRK multigene family. For example, this is the only GRK for …

[HTML][HTML] Group IV Phospholipase A2α Controls the Formation of Inter-Cisternal Continuities Involved in Intra-Golgi Transport

…, A DiPentima, A Trucco, P Zizza, S Mariggiò… - PLoS …, 2009 - journals.plos.org
The organization of intra-Golgi trafficking and the nature of the transport intermediates
involved (eg, vesicles, tubules, or tubular continuities) remain incompletely understood. It was …

Faciogenital dysplasia protein Fgd1 regulates invadopodia biogenesis and extracellular matrix degradation and is up-regulated in prostate and breast cancer

…, G Giacchetti, G Caldieri, F Attanasio, S Mariggio… - Cancer research, 2009 - AACR
Invadopodia are proteolytically active membrane protrusions that extend from the ventral
surface of invasive tumoral cells grown on an extracellular matrix (ECM). The core machinery …

[HTML][HTML] Role of G Protein-coupled Receptor Kinase 4 and ॆ-Arrestin 1 in Agonist-stimulated Metabotropic Glutamate Receptor 1 Internalization and Activation of …

…, A Picascia, E Barletta, M Storto, S Mariggio… - Journal of Biological …, 2003 - ASBMB
The metabotropic glutamate 1 (mGlu 1 ) receptor in cerebellar Purkinje cells plays a key
role in motor learning and motor coordination. Here we show that the G protein-coupled …

Reproducible surface-enhanced Raman quantification of biomarkers in multicomponent mixtures

AC De Luca, P Reader-Harris, M Mazilu, S Mariggio… - ACS …, 2014 - ACS Publications
Direct and quantitative detection of unlabeled glycerophosphoinositol (GroPIns), an abundant
cytosolic phosphoinositide derivative, would allow rapid evaluation of several malignant …

[HTML][HTML] A novel glycerophosphodiester phosphodiesterase, GDE5, controls skeletal muscle development via a non-enzymatic mechanism

…, N Ohshima, I Yoshizawa, Y Kamei, S Mariggiò… - Journal of biological …, 2010 - ASBMB
Mammalian glycerophosphodiester phosphodiesterases (GP-PDEs) have been identified
recently and shown to be implicated in several physiological functions. This study isolated a …

[HTML][HTML] New members of the mammalian glycerophosphodiester phosphodiesterase family: GDE4 and GDE7 produce lysophosphatidic acid by lysophospholipase D …

N Ohshima, T Kudo, Y Yamashita, S Mariggiò… - Journal of Biological …, 2015 - ASBMB
The known mammalian glycerophosphodiester phosphodiesterases (GP-PDEs) hydrolyze
glycerophosphodiesters. In this study, two novel members of the mammalian GP-PDE family, …