Cytotoxic activity of Brazilian Cerrado plants used in traditional medicine against cancer cell lines

…, LV Costa-Lotufo, R Grougnet, S Michel… - Journal of …, 2009 - Elsevier
The search for new anti-cancer drugs is one of the most prominent research areas of natural
products. Numerous active compounds isolated from Brazilian Cerrado plant species have …

Diversity-oriented synthesis of furo [3, 2-f] chromanes with antimycobacterial activity

L Alvey, S Prado, B Saint-Joanis, S Michel… - European journal of …, 2009 - Elsevier
We previously reported the synthesis and the antimycobacterial activity of 4-(7,7-dimethyl-7H-furo[3,2-f]chromen-2-yl)pyridine.
From this result, we sought to design simple synthetic …

[HTML][HTML] Collected mass spectrometry data on monoterpene indole alkaloids from natural product chemistry research

…, AM Le Ray, G Lewin, M Litaudon, L Mambu, S Michel… - Scientific Data, 2019 - nature.com
This Data Descriptor announces the submission to public repositories of the monoterpene
indole alkaloid database (MIADB), a cumulative collection of 172 tandem mass spectrometry (…

The synthesis and Angiotensin Converting Enzyme (ACE) inhibitory activity of chalcones and their pyrazole derivatives

M Bonesi, MR Loizzo, GA Statti, S Michel… - Bioorganic & medicinal …, 2010 - Elsevier
A series of chalcones (1–9) and pyrazoles (10–18) was prepared to investigate their potential
activity as Angiotensin I-Converting Enzyme (ACE) inhibitors. Their structures were verified …

A new synthetic access to furo [3, 2-f] chromene analogues of an antimycobacterial

…, S Prado, V Huteau, B Saint-Joanis, S Michel… - Bioorganic & medicinal …, 2008 - Elsevier
From the structure of 3,3-dimethyl-3H-benzofuro[3,2-f][1]-benzopyran, a selective in vitro
inhibitor of mycobacterial growth, we have undertaken a structure–activity relationship …

One-step semisynthesis of oleacein and the determination as a 5-lipoxygenase inhibitor

…, C Pergola, O Werz, AB Smith III, S Michel… - Journal of natural …, 2014 - ACS Publications
The dialdehydes oleacein (2) and oleocanthal (4) are closely related to oleuropein (1) and
ligstroside (3), the two latter compounds being abundant iridoids of Olea europaea. By …

Marked antitumor activity of a new potent acronycine derivative in orthotopic models of human solid tumors

…, V Malivet, C Chacun, M Jan, F Tillequin, S Michel… - Clinical Cancer …, 2001 - AACR
S 23906-1 is a novel acronycine derivative selected on the basis of its potency in vitro. We
investigated the antitumor activity of S 23906-1 against several murine transplantable tumors (…

A kaleidoscope of photosynthetic antenna proteins and their emerging roles

…, S Jansson, D Kirilovsky, R Kouřil, S Michel… - Plant …, 2022 - academic.oup.com
Photosynthetic light-harvesting antennae are pigment-binding proteins that perform one of
the most fundamental tasks on Earth, capturing light and transferring energy that enables life …

Synthesis and cytotoxic and antitumor activity of esters in the 1, 2-dihydroxy-1, 2-dihydroacronycine series

A Elomri, S Mitaku, S Michel… - Journal of medicinal …, 1996 - ACS Publications
Seven 1,2-dihydroxy-1,2-dihydroacronycine and 1,2-dihydroxy-1,2-dihydro-6-demethoxyacronycine
esters and diesters were synthesized via osmic oxidation of acronycine or 6-…

Antitumor Psoropermum Xanthones and Sarcomelicope Acridones: Privileged Structures Implied in DNA Alkylation

…, S Boutefnouchet, S Michel… - Journal of natural …, 2009 - ACS Publications
Fused isopropylfuran and dimethylpyran units are privileged structures present in numerous
bioactive natural products exemplified, in the field of anticancer drugs, by the …