… They regulate transmigration of monocytes across epithelial layer and possibly participate
in T cell activation. However, the main (and the most extensively studied) function of type II …

… in Rat-1 cells (38, 39) but does not constitutively activate it in COS-7 cells; oncogenicity of
gip2 cannot be tested in COS-7 cells, because they are already transformed by SV40 T antigen…

… Statistical analysis was performed using the t test. … Statistical significance between groups
was determined by the t … Statistical significance between groups was determined by the t test (p …

Adenosine has been reported to stimulate or inhibit the release of angiogenic factors
depending on the cell type examined. To test the hypothesis that differential expression of …

Integrins mediate cell adhesion to the extracellular matrix and transmit signals within the
cell that stimulate cell spreading, retraction, migration, and proliferation. The mechanism of …

The neurotransmitter serotonin (5-HT) plays an important role in the regulation of multiple
events in the CNS. We demonstrated recently a coupling between the 5-HT 4 receptor and the …

We tested the hypothesis that RhoA, a monomeric GTP-binding protein, induces association
of inositol trisphosphate receptor (IP 3 R) with transient receptor potential channel (TRPC1), …

The carboxyl terminus of the G protein a subunit is a key determinant of the fidelity of receptor
activation. We have previously shown that the Gqa subunit (aq) can be made to respond to …

… 2IMT significantly stimulated the JNK activities in the transfected cells; paired t-test, P<.05. …
stimulated the JNK activity as compared to their WT counterparts; paired t-test, P<.05. …

Microtubule (MT) destabilization promotes the formation of actin stress fibers and enhances
the contractility of cells; however, the mechanism involved in the coordinated regulation of …