The frontiers of bioimaging are currently being pushed toward the integration and correlation
of several modalities to tackle biomedical research questions holistically and across …

… that rac-[ 11 C]verapamil could be used for quantitative assessment of Pgp function at the
rat BBB by demonstrating a dose-dependent increase in the brain volume of distribution (V T ) …

A low‐molecular‐weight 18 F‐labeled tetrazine derivative was developed as a highly
versatile tool for bioorthogonal PET imaging. Prosthetic groups and undesired carrying of 18 F …

… outcome parameters, differences between baseline scans (before inhibitor administration)
and scans after inhibitor administration were tested using a two-tailed paired Student’s t test. …

The development of highly selective and fast biocompatible reactions for ligation and cleavage
has paved the way for new diagnostic and therapeutic applications of pretargeted in vivo …

The multidrug efflux transporter P-glycoprotein (P-gp) is expressed in high concentrations at
the blood–brain barrier (BBB) and is believed to be implicated in resistance to central …

Elacridar (ELC) and tariquidar (TQD) are generally thought to be nontransported inhibitors of
P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP), but recent data indicate …

A low-molecular-weight tetrazine labeled with the short-lived positron emitter carbon-11 was
developed as a bioorthogonal PET probe for pretargeted imaging. A method for efficient …

Purpose We evaluated the usefulness of small animal brain positron emission tomography (PET)
imaging with the amyloid-beta (Aβ) probe 2-(1-{6-[(2-[ 18 F]fluoroethyl)(methyl)amino]-2…

… administration were tested with a two-tailed paired Student’s t-test. For unpaired data, a
two-tailed Student’s t-test was used. The level of statistical significance was set to p < 0.05. …