User profiles for Takao Shimizu
Takao ShimizuNational Center for Global Health and Medicine Verified email at ri.ncgm.go.jp Cited by 63528 |
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
Corrigendum (2004) Adiponectin (also known as 30-kDa adipocyte complement-related
protein; Acrp30) 1 , 2 , 3 , 4 is a hormone secreted by adipocytes that acts as an antidiabetic 5 , …
protein; Acrp30) 1 , 2 , 3 , 4 is a hormone secreted by adipocytes that acts as an antidiabetic 5 , …
Cloning by functional expression of platelet-activating factor receptor from guinea-pig lung
…, H Okado, H Toh, K Ito, T Miyamoto, T Shimizu - Nature, 1991 - nature.com
PLATELET-activating factor (PAF), a unique phospholipid mediator, possesses potent
proinflammatory, smooth-muscle contractile and hypotensive activities, and appears to be crucial …
proinflammatory, smooth-muscle contractile and hypotensive activities, and appears to be crucial …
Prostaglandin F2α receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-β
…, Y Taguchi, K Chin, M Mishima, T Shimizu… - Nature medicine, 2009 - nature.com
Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by fibroblast
proliferation and excess deposition of collagen and other extracellular matrix (ECM) proteins, …
proliferation and excess deposition of collagen and other extracellular matrix (ECM) proteins, …
[HTML][HTML] A comprehensive classification system for lipids1
…, DW Russell, Y Seyama, W Shaw, T Shimizu… - Journal of lipid …, 2005 - ASBMB
Lipids are produced, transported, and recognized by the concerted actions of numerous
enzymes, binding proteins, and receptors. A comprehensive analysis of lipid molecules, "…
enzymes, binding proteins, and receptors. A comprehensive analysis of lipid molecules, "…
[HTML][HTML] Update of the LIPID MAPS comprehensive classification system for lipids1
In 2005, the International Lipid Classification and Nomenclature Committee under the
sponsorship of the LIPID MAPS Consortium developed and established a "Comprehensive …
sponsorship of the LIPID MAPS Consortium developed and established a "Comprehensive …
A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis
Leukotriene B 4 (LTB 4 ) 1 is a potent chemoattractant that is primarily involved in inflammation,
immune responses and host defence against infection 2 . LTB 4 activates inflammatory …
immune responses and host defence against infection 2 . LTB 4 activates inflammatory …
Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1
Adiponectin is an anti-diabetic adipokine. Its receptors possess a seven-transmembrane
topology with the amino terminus located intracellularly, which is the opposite of G-protein-…
topology with the amino terminus located intracellularly, which is the opposite of G-protein-…
Role of cytosolic phospholipase A2 in allergic response and parturition
…, K Maki, K Ikuta, Y Ouchi, J Miyazaki, T Shimizu - Nature, 1997 - nature.com
Phospholipase A 2 (PLA 2 ) comprises a superfamily of enzymes that hydrolyse the ester
bond of phospholipids at the sn-2 position 1 , 2 , 3 . Among the members of this superfamily, …
bond of phospholipids at the sn-2 position 1 , 2 , 3 . Among the members of this superfamily, …
A Second Leukotriene B4 Receptor, Blt2: A New Therapeutic Target in Inflammation and Immunological Disorders
…, K Kato, K Terawaki, T Izumi, T Shimizu - The Journal of …, 2000 - rupress.org
Leukotriene B 4 (LTB 4 ) is a potent chemoattractant and activator of both granulocytes and
macrophages. The actions of LTB 4 appear to be mediated by a specific G protein–coupled …
macrophages. The actions of LTB 4 appear to be mediated by a specific G protein–coupled …
[HTML][HTML] Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family
Lysophosphatidic acid (LPA) is a bioactive lipid mediator with diverse physiological and
pathological actions on many types of cells. LPA has been widely considered to elicit its …
pathological actions on many types of cells. LPA has been widely considered to elicit its …