User profiles for Tanu Parmar
 | Tanu ParmarDuke University Verified email at duke.edu Cited by 397 |
[HTML][HTML] Protein profiling of human endometrial tissues in the midsecretory and proliferative phases of the menstrual cycle
T Parmar, S Gadkar-Sable, L Savardekar, R Katkam… - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To identify the proteins displaying differential expression in midsecretory phase
endometrium as compared with proliferative phase endometrium. DESIGN: Prospective …
endometrium as compared with proliferative phase endometrium. DESIGN: Prospective …
Lipocalin 2 plays an important role in regulating inflammation in retinal degeneration
T Parmar, VM Parmar, L Perusek… - The Journal of …, 2018 - journals.aai.org
It has become increasingly important to understand how retinal inflammation is regulated
because inflammation plays a role in retinal degenerative diseases. Lipocalin 2 (LCN2), an …
because inflammation plays a role in retinal degenerative diseases. Lipocalin 2 (LCN2), an …
[HTML][HTML] A2E-associated cell death and inflammation in retinal pigmented epithelial cells from human induced pluripotent stem cells
VM Parmar, T Parmar, E Arai, L Perusek, A Maeda - Stem cell research, 2018 - Elsevier
Accumulation of lipofuscin in the retinal pigmented epithelium (RPE) is observed in retinal
degenerative diseases including Stargardt disease and age-related macular degeneration. Bis…
degenerative diseases including Stargardt disease and age-related macular degeneration. Bis…
Protective effects of flavonoids in acute models of light-induced retinal degeneration
Degeneration of photoreceptors caused by excessive illumination, inherited mutations, or
aging is the principal pathology of blinding diseases. Pharmacological compounds that …
aging is the principal pathology of blinding diseases. Pharmacological compounds that …
Flavonoids improve the stability and function of P23H rhodopsin slowing down the progression of retinitis pigmentosa in mice
The balanced homeostasis of the G protein–coupled receptor (GPCR), rhodopsin (Rho), is
required for vision. Misfolding mutations in Rho cause photoreceptor death, leading to retinitis …
required for vision. Misfolding mutations in Rho cause photoreceptor death, leading to retinitis …
[HTML][HTML] Flavonoids enhance rod opsin stability, folding, and self-association by directly binding to ligand-free opsin and modulating its conformation
Rhodopsin (Rho) is a visual G protein–coupled receptor expressed in the rod photoreceptors
of the eye, where it mediates transmission of a light signal into a cell and converts this …
of the eye, where it mediates transmission of a light signal into a cell and converts this …
[HTML][HTML] Di-retinoid-pyridinium-ethanolamine (A2E) accumulation and the maintenance of the visual cycle are independent of Atg7-mediated autophagy in the retinal …
Autophagy is an evolutionarily conserved catabolic mechanism that relieves cellular stress
by removing/recycling damaged organelles and debris through the action of lysosomes. …
by removing/recycling damaged organelles and debris through the action of lysosomes. …
[HTML][HTML] Acute stress responses are early molecular events of retinal degeneration in Abca4−/− Rdh8−/− mice after light exposure
Purpose: Mice lacking ATP-binding cassette transporter 4 (ABCA4) and retinol dehydrogenase
8 (RDH8) mimic features of human Stargardt disease and age-related macular …
8 (RDH8) mimic features of human Stargardt disease and age-related macular …
Retinoid analogs and polyphenols as potential therapeutics for age-related macular degeneration
Progressive retinal degeneration manifesting as age-related macular degeneration (AMD) in
the elderly affects millions of individuals worldwide. Among various blinding diseases, AMD …
the elderly affects millions of individuals worldwide. Among various blinding diseases, AMD …
[HTML][HTML] Galanin receptor 3− A new pharmacological target in retina degeneration
The neuropeptide galanin receptor 3 (GALR3) is a class AG protein-coupled receptor (GPCR)
broadly expressed in the nervous system, including the retina. GALR3 is involved in the …
broadly expressed in the nervous system, including the retina. GALR3 is involved in the …