User profiles for Tin-Yun Ho

Tin-Yun Ho

China Medical University, Taiwan
Verified email at mail.cmu.edu.tw
Cited by 6037

Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction

TY Ho, SL Wu, JC Chen, CC Li, CY Hsiang - Antiviral research, 2007 - Elsevier
Severe acute respiratory syndrome (SARS) is an emerging infectious disease caused by a
novel coronavirus (SARS-CoV). SARS-CoV spike (S) protein, a type I membrane-bound …

Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds

CW Lin, FJ Tsai, CH Tsai, CC Lai, L Wan, TY Ho… - Antiviral research, 2005 - Elsevier
The 3C-like protease (3CL pro ) of SARS-coronavirus mediates the proteolytic processing of
replicase polypeptides 1a and 1ab into functional proteins, becoming an important target for …

Ferulic acid provides neuroprotection against oxidative stress-related apoptosis after cerebral ischemia/reperfusion injury by inhibiting ICAM-1 mRNA expression in …

CY Cheng, SY Su, NY Tang, TY Ho, SY Chiang… - Brain research, 2008 - Elsevier
Our previous studies have shown that ferulic acid (4-hydroxy-3-methoxycinnamic acid, FA)
inhibits intercellular adhesion molecule-1 (ICAM-1) expression in the ischemic striatum after 2 …

[HTML][HTML] 5-Fluorouracil Induced Intestinal Mucositis via Nuclear Factor-κB Activation by Transcriptomic Analysis and In Vivo Bioluminescence Imaging

CT Chang, TY Ho, H Lin, JA Liang, HC Huang, CC Li… - PloS one, 2012 - journals.plos.org
5-Fluorouracil (5-FU) is a commonly used drug for the treatment of malignant cancers.
However, approximately 80% of patients undergoing 5-FU treatment suffer from gastrointestinal …

Ferulic acid reduces cerebral infarct through its antioxidative and anti-inflammatory effects following transient focal cerebral ischemia in rats

CY Cheng, TY Ho, EJ Lee, SY Su, NY Tang… - The American journal …, 2008 - World Scientific
Both Angelica sinensis (Oliv.) Diels (AS) and Ligusticum chuanxiong Hort. (LC) have been
used to treat stroke in traditional Chinese medicine for centuries. Ferulic acid (FA), a …

Berberine suppresses inflammatory agents-induced interleukin-1β and tumor necrosis factor-α productions via the inhibition of IκB degradation in human lung cells

…, JC Chen, CY Hsiang, SL Wu, HC Wu, TY Ho - Pharmacological …, 2007 - Elsevier
Pulmonary inflammation is a characteristic of many lung diseases. Increased levels of pro-inflammatory
cytokines, such as interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α), …

Ginger and Its Bioactive Component Inhibit Enterotoxigenic Escherichia coli Heat-Labile Enterotoxin-Induced Diarrhea in Mice

…, LJ Huang, SL Wu, SC Kuo, TY Ho… - Journal of agricultural …, 2007 - ACS Publications
Ginger is one of the most commonly used fresh herbs and spices. Enterotoxigenic Escherichia
coli heat-labile enterotoxin (LT)-induced diarrhea is the leading cause of infant death in …

Toona sinensis and its major bioactive compound gallic acid inhibit LPS-induced inflammation in nuclear factor-κB transgenic mice as evaluated by in vivo …

CY Hsiang, YC Hseu, YC Chang, KJS Kumar, TY Ho… - Food chemistry, 2013 - Elsevier
In the present study, we investigated the anti-inflammatory effects of a nutritious vegetable
Toona sinensis (leaf extracts, TS) and its major bioactive compound gallic acid (GA) by …

Ginger extract and zingerone ameliorated trinitrobenzene sulphonic acid-induced colitis in mice via modulation of nuclear factor-κB activity and interleukin-1β …

CY Hsiang, HY Lo, HC Huang, CC Li, SL Wu, TY Ho - Food chemistry, 2013 - Elsevier
Ginger is a commonly used spice with anti-inflammatory potential. Colitis is the common
pathological lesion of inflammatory bowel diseases. In this study, we investigated the …

Vanillin inhibits matrix metalloproteinase-9 expression through down-regulation of nuclear factor-κB signaling pathway in human hepatocellular carcinoma cells

JA Liang, SL Wu, HY Lo, CY Hsiang, TY Ho - Molecular pharmacology, 2009 - ASPET
Vanillin has been reported to exhibit anti-invasive and antimetastatic activities by suppressing
the enzymatic activity of matrix metalloproteinase-9 (MMP-9). However, the underlying …