Insulin secretagogues (sulfonylureas and glinides) increase insulin secretion by closing the
ATP-sensitive K + channel (K ATP channel) in the pancreatic β-cell membrane. K ATP …

… 40); however, at 10 mM Ba2+ (a concentration that induces maximum vascular tone), the
vasorelaxant effect of cromakalim is abolished (Quast, U., unpublished observations). The …

Total Body Irradiation (TBI) is one main component in the interdisciplinary treatment of widely
disseminated malignancies predominantly of haematopoietic diseases. Combined with …

We have developed dosemeters based on plastic scintillators for a variety of applications in
radiation therapy. The dosemeters consist basically of a tissue‐substituting scintillator probe, …

In treatment of acute leukaemia and other disseminated diseases, high dose total body
irradiation (TBI)combined with intensive chemotherapy and bone marrow transplantation (BMT) …

… Figure 1B shows the effect of ATP in the presence of the ARS using 5 u ml −1 creatine …
This possibility was tested by scaling up the ARS 10 fold (creatine kinase 50 u ml −1 , creatine …

Opening of plasmalemmal K+ channels leads to cellular hyperpolarization which, in excitable
tissues possessing voltage‐dependent Ca 2+ channels, prevents the opening of such …

Aims/hypothesis Sulfonylureas and glinides close beta cell ATP-sensitive K + (K ATP ) channels
to increase insulin release; the concomitant closure of cardiovascular K ATP channels, …

Diazoxide caused an increase in 86Rb+ efflux from the rat aorta and portal vein and inhibited
spontaneous activity of the latter at concentrations 100 times higher than the K+ channel …

Potassium channel opening is a physiological mechanism which excitable cells exploit to
maintain or restore their resting state. Thus drugs that open vascular potassium channels have …