In 2000, the National Institute of Health launched the National Nanotechnology Initiative to
support, coordinate, and advance research and development of nanoscale projects. The …

Since compounds targeting mitochondria exhibit diverse accumulation mechanisms and
chemical features, various questions arise. Do such “mitochondriotropics” have a characteristic …

In part I of this review we assessed nanoscience-related definitions as applied to
pharmaceuticals and we discussed all 43 currently approved drug formulations, which are widely …

The Protein Data Bank (PDB; http://www.rcsb.org/pdb/ ) is the single worldwide archive of
structural data of biological macromolecules. This paper describes the goals of the PDB, the …

… it can meet new emerging challenges posed by researchers and educators in the field of
structural bioinformatics (Weissig & Bourne, 2002 [Weissig, H. & Bourne, PE (2002). Acta Cryst. …

To achieve an efficient intracellular drug and DNA delivery, attempts were made to target
microparticulate drug carriers into cytoplasm bypassing the endocytotic pathway. TAT peptides …

Since the first edition of" Liposomes-A Practical Approach" was published in 1990, Liposome
technology has become a highly successful and rapidly developing area of preclinical and …

The cytoplasmic domain of classical cadherins is tightly associated with three proteins termed
α-, β- and γ-catenin. These accessory proteins are of central importance for the adhesive …

The PDB has created systems for the processing, exchange, query, and distribution of data
that will enable many aspects of high throughput structural genomics.

The central role of protein kinases in signal transduction pathways has generated intense
interest in targeting these enzymes for a wide range of therapeutic indications. Here we report …