Plant volatiles: recent advances and future perspectives

N Dudareva, F Negre, DA Nagegowda… - Critical reviews in plant …, 2006 - Taylor & Francis
<p>Volatile compounds act as a language that plants use for their communication and
interaction with the surrounding environment. To date, a total of 1700 volatile compounds have …

Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors

A Negre‐Salvayre, C Coatrieux… - British journal of …, 2008 - Wiley Online Library
Reactive carbonyl compounds (RCCs) formed during lipid peroxidation and sugar glycoxidation,
namely Advanced lipid peroxidation end products (ALEs) and Advanced Glycation end …

Pathological aspects of lipid peroxidation

A Negre-Salvayre, N Auge, V Ayala, H Basaga… - Free radical …, 2010 - Taylor & Francis
Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular
and cellular dysfunction that plays a major role in ageing and most age-related and …

[HTML][HTML] Evolution of genes and genomes on the Drosophila phylogeny

…, K Montooth, SM Mount, X Mu, E Myers, B Negre… - Nature, 2007 - hal.science
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

M Cavazzana-Calvo, E Payen, O Negre, G Wang… - Nature, 2010 - nature.com
The β-haemoglobinopathies are the most prevalent inherited disorders worldwide. Gene
therapy of β-thalassaemia is particularly challenging given the requirement for massive …

[HTML][HTML] DFTB+, a software package for efficient approximate density functional theory based atomistic simulations

…, RJ Maurer, SK Min, I Mitchell, C Negre… - The Journal of …, 2020 - pubs.aip.org
DFTB+ is a versatile community developed open source software package offering fast and
efficient methods for carrying out atomistic quantum mechanical simulations. By …

A role for uncoupling protein‐2 as a regulator of mitochondrial hydrogen peroxide generation

A Nègre‐Salvayre, C Hirtz, G Carrera… - The FASEB …, 1997 - Wiley Online Library
According to the state of mitochondrial respiration, the respiratory chain generates
superoxide anions converted into hydrogen peroxide. Two uncoupling proteins (UCP) able to …

Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

…, J Ernst, PV Kharchenko, P Kheradpour, N Negre… - Science, 2010 - science.org
To gain insight into how genomic information is translated into cellular and developmental
programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) …

[HTML][HTML] Gene therapy in a patient with sickle cell disease

…, T Lefebvre, RW Ross, O Negre… - … England Journal of …, 2017 - Mass Medical Soc
<p id="p001">Sickle cell disease results from a homozygous missense mutation in the β-globin
gene that causes polymerization of hemoglobin S. Gene therapy for patients with this …

Gene therapy in patients with transfusion-dependent β-thalassemia

…, E Vichinsky, S Soni, G Veres, O Negre… - … England Journal of …, 2018 - Mass Medical Soc
Background Donor availability and transplantation-related risks limit the broad use of
allogeneic hematopoietic-cell transplantation in patients with transfusion-dependent β-thalassemia…