Viral subversion of the immune system

D Tortorella, BE Gewurz, MH Furman… - Annual review of …, 2000 - annualreviews.org
This review describes the diverse array of pathways and molecular targets that are used by
viruses to elude immune detection and destruction. These include targeting of pathways for …

Diagnostic value of cerebrospinal fluid neurofilament light protein in neurology: a systematic review and meta-analysis

…, A Svenningsson, R Tortelli, C Tortorella… - JAMA …, 2019 - jamanetwork.com
Importance Neurofilament light protein (NfL) is elevated in cerebrospinal fluid (CSF) of a
number of neurological conditions compared with healthy controls (HC) and is a candidate …

Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation

…, C Impallomeni, E Germano, G Tortorella… - Archives of general …, 2009 - jamanetwork.com
Context Results of comparative genomic hybridization studies have suggested that rare copy
number variations (CNVs) at numerous loci are involved in the cause of mental retardation, …

Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial

VM Ranieri, PM Suter, C Tortorella, R De Tullio… - Jama, 1999 - jamanetwork.com
ContextStudies have shown that an inflammatory response may be elicited by mechanical
ventilation used for recruitment or derecruitment of collapsed lung units or to overdistend …

Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

EJHJ Wiertz, D Tortorella, M Bogyo, J Yu, W Mothes… - Nature, 1996 - nature.com
The human cytomegalovirus genome encodes proteins that trigger destruction of newly
synthesized major histocompatibility complex (MHC) class I molecules. The human …

Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins

MD Tortorella, TC Burn, MA Pratta, I Abbaszade… - Science, 1999 - science.org
We purified, cloned, and expressed aggrecanase, a protease that is thought to be
responsible for the degradation of cartilage aggrecan in arthritic diseases. Aggrecanase-1 [a …

Disease‐modifying therapies and coronavirus disease 2019 severity in multiple sclerosis

…, A Zito, A Sartori, B Giometto, C Tortorella… - Annals of …, 2021 - Wiley Online Library
Objective This study was undertaken to assess the impact of immunosuppressive and
immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID‐19) in people …

Attention deficit and hyperactivity disorders in the offspring of mothers exposed to mild-moderate iodine deficiency: a possible novel iodine deficiency disorder in …

…, M Moleti, M Sidoti, G Tortorella… - The Journal of …, 2004 - academic.oup.com
Over a period of almost 10 yr, we carried out a prospective study of the neuropsychological
development of the offspring of 16 women from a moderately iodine-deficient area (area A) …

Exploring Industry 4.0 technologies to enable circular economy practices in a manufacturing context: A business model proposal

…, L Rocha-Lona, G Tortorella - Journal of …, 2019 - emerald.com
Purpose The purpose of this paper is to explore how rising technologies from Industry 4.0
can be integrated with circular economy (CE) practices to establish a business model that …

Implementation of Industry 4.0 and lean production in Brazilian manufacturing companies

GL Tortorella, D Fettermann - International Journal of Production …, 2018 - Taylor & Francis
The adoption of Industry 4.0 technologies has been deemed as a strategy to increase product
quality and make manufacturing processes more efficient. However, the way that these …