Comparison of the potential multiple binding modes of bicyclam, monocylam, and noncyclam small-molecule CXC chemokine receptor 4 inhibitors

RSY Wong, V Bodart, M Metz, J Labrecque… - Molecular …, 2008 - ASPET
CXC chemokine receptor (CXCR)4 is an HIV coreceptor and a chemokine receptor that
plays an important role in several physiological and pathological processes, including …

Pharmacology of AMD3465: a small molecule antagonist of the chemokine receptor CXCR4

V Bodart, V Anastassov, MC Darkes, SR Idzan… - Biochemical …, 2009 - Elsevier
CXCR4 is widely expressed in multiple cell types, and is involved in neonatal development,
hematopoiesis, and lymphocyte trafficking and homing. Disruption of the CXCL12/CXCR4 …

Design and synthesis of pyridin-2-ylmethylaminopiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication

…, M Sartori, M Metz, R Mosi, K Nelson, V Bodart… - Bioorganic & medicinal …, 2011 - Elsevier
A series of CCR5 antagonists were optimized for potent inhibition of R5 HIV-1 replication in
peripheral blood mononuclear cells. Compounds that met acceptable ADME criteria, …

Design of substituted imidazolidinylpiperidinylbenzoic acids as chemokine receptor 5 antagonists: potent inhibitors of R5 HIV-1 replication

…, R MacFarland, R Mosi, V Bodart… - Journal of Medicinal …, 2013 - ACS Publications
The redesign of the previously reported thiophene-3-yl-methyl urea series, as a result of
potential cardiotoxicity, was successfully accomplished, resulting in the identification of a novel …

Mitigating hERG inhibition: design of orally bioavailable CCR5 antagonists as potent inhibitors of R5 HIV-1 replication

…, M Metz, R MacFarland, R Mosi, V Bodart… - ACS Medicinal …, 2012 - ACS Publications
A series of CCR5 antagonists representing the thiophene-3-yl-methyl ureas were designed
that met the pharmacological criteria for HIV-1 inhibition and mitigated a human ether-a-go-…

[BOOK][B] Contribution à l'étude des mécanismes cellulaires responsables du contrôle de la biosynthèse de l'aldostérone

V Bodart - 1997 - central.bac-lac.gc.ca
… de doctorat de M"' Veronlque Bodart, j'autorise le microfilmage et la diffusion de cette thise.
… de doctorat de M"' Veronique Bodart, j'autorise Ie microfilmage et la diffusion de cette these. …

[PDF][PDF] Understanding the interactions between CXCR4 and AMD11070, a first-in-class small-molecule antagonist of the HIV coreceptor

R Wong, V Bodart, M Metz, J Labrecque… - 14th Conference on …, 2007 - researchgate.net
Background: AMD11070 is a first-in-class, bioavailable small molecule antagonist against
the HIV coreceptor CXCR4. An ongoing safety and dose-finding study has demonstrated the …

Cesarean during labor: Is induction a risk factor for complications?

V Delporte, A Grabarz, N Ramdane, S Bodart… - Journal of Gynecology …, 2019 - Elsevier
Introduction Evaluate the impact of labor induction on maternal complications following
caesarean section during labor. Material and methods Retrospective, single-center study …

[PDF][PDF] Les Belges sont-ils tous égaux face à l'inflation?

V Bodart, J Hindriks - 2006 - sites.uclouvain.be
… Nous remercions surtout Madame Véronique Renard, de l'Institut National de la Statistique,
… Vincent Bodart est professeur au département d'économie de l'UCL et directeur du Service d…

[CITATION][C] Groupe des juristes

B Bodart - 2011 - Bastien Bodart